業績

  • 2022年

    1 Huyghe J, Priem D, Van Hove L, Gilbert B, Fritsch J, Uchiyama Y, Hoste E, van Loo G, Bertrand MJM: ATG9A prevents TNF cytotoxicity by an unconventional lysosomal targeting pathway. Science. 2022, 378:1201-1207.
    2 Sou YS, Yamaguchi J, Kameda H, Masuda K, Maeda Y, Uchiyama Y, Koike M: GPHR-mediated acidification of the Golgi lumen is essential for cholesterol biosynthesis in the brain. FEBS Lett. 2022, 596:2873-2888.
    3 Murakami S, Ohki-Hamazaki H, Uchiyama Y: Olfactory placode generates a diverse population of neurons expressing GnRH, somatostatin mRNA, neuropeptide Y, or calbindin in the chick forebrain. J Comp Neurol. 2022, 530:2977-2993.
    4 Suzuki C, Yamaguchi J, Sanada T, Oliva Trejo JA, Kakuta S, Shibata M, Tanida I, Uchiyama Y: Lack of Cathepsin D in the central nervous system results in microglia and astrocyte activation and the accumulation of proteinopathy-related proteins. Sci Rep. 2022, 12:11662.
    5 Sanada T, Yamaguchi J, Furuta Y, Kakuta S, Tanida I, Uchiyama Y: In-resin CLEM of Epon-embedded cells using proximity labeling. Sci Rep. 2022, 12:11130.
    6 Ochiai Y, Suzuki C, Segawa K, Uchiyama Y, Nagata S: Inefficient development of syncytiotrophoblasts in the Atp11a-deficient mouse placenta. Proc Natl Acad Sci U S A. 2022, 119:e2200582119.
    7 Suzuki A, Iwaya C, Ogata K, Yoshioka H, Shim J, Tanida I, Komatsu M, Tada N, Iwata J: Impaired GATE16-mediated exocytosis in exocrine tissues causes Sjögren’s syndrome-like exocrinopathy. Cell Mol Life Sci. 2022, 79:307.
    8 Guidelines for cadaver dissection in education and research of clinical medicine (The Japan Surgical Society and The Japanese Association of Anatomists). Shichinohe T, Kondo T, Date H, Hiramatsu M, Hirano S, Ide C, Iwanaga T, Izawa Y, Kikuta A, Kobayashi E, Matsui Y, Nohara Y, Shibata T, Shirakawa Y, Suzuki T, Takahashi H, Taneichi H, Tsurumoto T, Uchiyama Y, Watanabe M, Yaginuma H, Yamaguchi K, Yoshida K. Anat Sci Int. 2022, 97(3):235-240.
    9 Guidelines for cadaver dissection in education and research of clinical medicine (The Japan Surgical Society and The Japanese Association of Anatomists). Shichinohe T, Kondo T, Date H, Hiramatsu M, Hirano S, Ide C, Iwanaga T, Izawa Y, Kikuta A, Kobayashi E, Matsui Y, Nohara Y, Shibata T, Shirakawa Y, Suzuki T, Takahashi H, Taneichi H, Tsurumoto T, Uchiyama Y, Watanabe M, Yaginuma H, Yamaguchi K, Yoshida K. Surg Today. 2022, 52(7):989-994.
    10 Nakajima K., Osada T., Ogawa A., Tanaka M., Oka S., Kamagata K., Aoki S., Oshima Y., Tanaka S., Konishi S. Prefrontal-striatal circuit performs an alternative processing for response inhibition in humans. Cell Reports, 40, 111197, 2022
    11 Osada T., Nakajima K., Ogawa A., Oka S., Kamagata K., Aoki S., Oshima Y., Tanaka S., Konishi S. Distributions of cortical depth of the index finger region in the M1: A representative depth parameter for transcranial ultrasound stimulation. Brain Stimulation, 15, 1348-1350, 2022
    12 Ogawa A., Osada T., Tanaka M., Suda A., Nakajima K., Oka S., Kamagata K., Aoki S., Oshima Y., Tanaka S., Hattori N., Konishi S. Hypothalamic interaction with reward-related regions during subjective evaluation of foods. Neuroimage, 264, 119744, 2022
    13 Hidenori Sugano, Yasushi Iimura, Hiroharu Suzuki, Samantha Tamrakar, Takumi Mitsuhashi, Takuma Higo, Tetsuya Ueda, Kazuki Nishioka, Kostadin Karagiozov, Madoka Nakajima.Can intraoperative electrocorticography be used to minimize the extent of resection in patients with temporal lobe epilepsy associated with hippocampal sclerosis?.J Neurosurg, 2022; 3:1-8.
    14 Joni Hänninen, Madoka Nakajima, Aleksi Vanninen, Santtu Hytönen, Jaana Rummukainen, Anne M. Koivisto, Olli-Pekka Kämäräinen, Juha E. Jääskeläinen, Hilkka Soininen, Anna Sutela, Ritva Vanninen, Mikko Hiltunen, Irina Alafuzoff, Ville Leinonen, Tuomas Rauramaa.Neuropathological findings in possible normal pressure hydrocephalus:  A post-mortem study of 29 cases with lifelines.Free Neuropathology, 2022; https://www.uni-muenster.de/Ejournals/index.php/fnp/article/view/3331
    15 Anri Hattori, Taiji Tsunemi, Yuta Ishiguro, Ayami Okuzumi, Taku Hatano, Kaito Kawamura, Madoka Nakajima, Masakazu Miyajima, Nobutaka Hattori.The effectiveness of cerebrospinal fluid shunt surgery for idiopathic normal pressure hydrocephalus with comorbid Parkinson’s disease/PD dementia.J Neurosurg, 2022; 11:1-8
    16 Junko Kikuta, Koji Kamagata, Toshiaki Taoka, Kaito Takabayashi, Wataru Uchida, Yuya Saito, Christina Andica, Akihiko Wada, Kaito Kawamura, Chihiro Akiba, Madoka Nakajima, Masakazu Miyajima, Shinji Naganawa and Shigeki Aoki.Water Diffusivity Changes Along the Perivascular Space after.Front Neurol, 2022; 13:843883 Lumboperitoneal Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus.
    17 Hanbing Xu, Masakazu Miyajima, Madoka Nakajima, Ikuko Ogino, Kaito Kawamura, Chihiro Akiba, Chihiro Kamohara, Eri Nakamura, Nobuhiro Tada, Hajime Arai, Akihide Kondo:Deletion of Ptpn20 is a genetic risk factor for hydrocephalus in H-Tx rats.Fluids Barriers CNS, 2022;  3;19(1):39.
    18 Tamrakar Samantha, Iimura Yasushi; Suzuki, Hiroharu; Mitsuhashi, Takumi; Ueda, Tetsuya; Nishioka, Kazuki; Karagiozov, Kostadin; Nakajima, Madoka; Miao, Yao; Tanaka, Toshihisa; Sugano, Hidenori.Higher phase-amplitude coupling between ripple and slow oscillations indicates the distribution of epileptogenicity in temporal lobe epilepsy with hippocampal sclerosis.Seizure, 2022;  29; 100:1-7
    19 Kostadin L. Karagiozov, Ville Leinonen, Masakazu Miyajima, Madoka Nakajima.EDITORIAL: Towards a Better Understanding of the Pathophysiology and Clinical Management of Idiopathic Normal Pressure Hydrocephalus.EDITORIAL: Towards a Better Understanding of the Pa
    20 Kosuke Fukumori, Noboru Yoshida, Hidenori Sugano, Madoka Nakajima, Toshihisa Tanaka.Satelight: Self-attention-based model for epileptic spike detection from multi-electrode EEG.J Neural Eng, 2022; 19(5).  doi: 10.1088/1741-2552/ac9050.
    21 Yuzaburo Shimizu, Joy Gumin, Feng Gao, Anwar Hossain, Elizabeth J. Shpall, Akihide Kondo, Brittany C. Parker Kerrigan, Jing Yang, Daniel Ledbetter, Juan Fueyo, Candelaria Gomez-Manzano, and Frederick F. Lang.Characterization of patient-derived bone marrow human mesenchymal stem cells as oncolytic virus carriers for the treatment of glioblastoma.J Neurosurg. 2021 Aug 27;136(3):757-767
    22 Noritaka Komune , Tomoharu Suzuki , Yusuke Miyamoto , Joe Iwanaga , Satoshi Matsuo , Osamu Akiyama , R Shane Tubbs , Takashi Nakagawa.Anatomy of small canals around the jugular foramen: Special reference to Jacobson’s and Arnold’s nerves.Clin Anat . 2023 May;36(4):599-606. doi: 10.1002/ca.23998. Epub 2023 Jan 9.
    23 Takami H, Satomi K, Ichimura K Prognostic factors of CNS germinomas; histopathological analyses on 114 cases from the iGCT consortium, doi.org/10.14791/btrt.2022.10.F-2537
    24 T Mimori, T Shukuya, R Ko, Y Okuma, T Koizumi, H Imai, Y Takiguchi, E Miyauchi, H Kagamu, T Sugiyama, K Azuma, Y Namba, M Yamasaki, H Tanaka,  Y Takashima,  S Soda,  O Ishimoto,  N Koyama, K Kobayashi, K Takahashi. Clinical Significance of Tumor Markers for Advanced Thymic Carcinoma: A Retrospective Analysis from the NEJ023 Study. Cancers (Basel)., 2022; 14(2): 331.
    25 H Tad, T Mitsudomi, T Misumi, K Sugio, M Tsuboi, I Okamoto, Y Iwamoto, N Sakakura, S Sugawara, S Atagi,  T Takahashi, H Hayashi, M Okada, H Inokawa, H Yoshioka, K Takahashi, M Higashiyama, I Yoshino, K Nakagawa; West Japan Oncology Group. Randomized Phase III Study of Gefitinib Versus Cisplatin Plus Vinorelbine for Patients With Resected Stage II-IIIA Non-Small-Cell Lung Cancer With EGFR Mutation (IMPACT). J Clin Oncol., 2022; 40(3): 231-241.
    26 A Wirawan, K Tajima, F Takahashi, Y Mitsuishi,  W Winardi, M Hidayat, D Hayakawa, N Matsumoto, K Izumi, T Asao, R Ko, N Shimada, K Takamochi, K Suzuki, M Abe,  O Hino, Y Sekido, K Takahashi. A Novel Therapeutic Strategy Targeting the Mesenchymal Phenotype of Malignant Pleural Mesothelioma By Suppressing LSD1. Mol Cancer Res., 2022; 20(1): 127-138.
    27 H Jo, T Yoshida, H Horinouchi, S Yagishita, Y Matsumoto, Y Shinno, Y Okum, Y Goto, N Yamamoto, K Takahashi, N Motoi, Y Ohe. Prognostic significance of cachexia in advanced non-small cell lung cancer patients treated with pembrolizumab. Cancer Immunol Immunother., 2022; 71(2):387-398.
    28 T Miyawaki, T Naito, M Yabe,  H Kodama, N Nishioka, E Miyawaki, N Mamesaya, H Kobayashi, S Omori, K Wakuda, A Ono, H Kenmotsu, H Murakami, K Mori, H Harada, K Takahashi, T Takahashi. Impact of weight loss on treatment with PD-1/PD-L1 inhibitors plus chemotherapy in advanced non-small-cell lung cancer. Support Care Cancer. Support Care Cancer., 2022 ;30(2): 1633-1641.
    29 K Enomoto, Y Eguchi, T Sato,  M Norimoto, M Inoue, A Watanabe, T Sakai, M Yoneyama, Y Aoki, S Orita, M Narita, K Inage, Y Shiga, T Umimura, M Sato, M Suzuki, H Takaoka, N Mizuki, G Kim, T Hozumi, N Hirosawa, T Furuya,  S Maki, J Nakamura, S Hagiwara, M Koda, T Akazawa, H Takahashi, K Takahashi, S Ohtori. Usefulness of Simultaneous Magnetic Resonance Neurography and Apparent T2 Mapping for the Diagnosis of Cervical Radiculopathy. Asian Spine J., 2022; 16(1): 47-55.
    30 E Miyawaki, H Kenmotsu, Y Shintani, I Sekine, T Shukuya, K Takayama, A Inoue, I Okamoto, K Kiura, K Takahashi, Yamamoto N, Kawaguchi T, Miyaoka E, Yoshino I, Date H. Efficacy of platinum agents for stage III non-small-cell lung cancer following platinum-based chemoradiotherapy: a retrospective study. BMC Cancer., 2022; 22(1): 342.
    31 SS Shimamura, T Shukuya, T Asao, D Hayakawa, K Kurokawa, S Xu, K Miura, Y Mitsuishi, K Tajima, R Shibayama, N Shimada, F Takahashi, K Takahashi. Survival past five years with advanced, EGFR-mutated or ALK-rearranged non-small cell lung cancer-is there a “tail plateau” in the survival curve of these patients? BMC Cancer., 2022; 22(1): 323.
    32 S Ueda, J Ito, N Harada, S Harada, H Sasano, Y Sandhu, Y Tanabe, S Abe, S Shiota, Y Kodama, T Nagaoka, F Makino, A Chiba, H Akiba, R Atsuta, A Miyake, K Takahashi. Effect of Japanese Cedar Pollen Sublingual Immunotherapy on Asthma Patients with Seasonal Allergic Rhinitis Caused by Japanese Cedar Pollen. Biomolecules., 2022; 12(4): 518.
    33 S Xu, T Shukuya, J Tamura, S Shimamura, K Kurokawa, K Miura, T Miyawaki, D Hayakawa, T Asao, K Yamamoto, K Takahashi. Heterogeneous Outcomes of Immune Checkpoint Inhibitor Rechallenge in Patients With NSCLC: A Systematic Review and Meta-Analysis. JTO Clin Res Rep., 2022; 3(4): 100309.
    34 K Nakamura, H Nakayama, S Sasaki, K Takahashi, K Iwabuchi. Mycobacterium avium-intracellulare complex promote release of pro-inflammatory enzymes matrix metalloproteinases by inducing neutrophil extracellular trap formation. Sci Rep., 2022; 12(1): 5181
    35 Y Yan, T Naito, Y Tabe, K Ito, S Nojiri, GA Deshpande, K Seyama, K Takahashi. Increased delta variant SARS-CoV-2 infections in a highly vaccinated medical center in Japan. Vaccine., 2022;  40(23): 3103-3108.
    36 NA Nitta, T Sato, M Komura, H Yoshikawa, Y Suzuki, A Mitsui, E Kuwasaki, F Takahashi, Y Kodama, K Seyama, K Takahashi. Exposure to the heated tobacco product IQOS generates apoptosis-mediated pulmonary emphysema in murine lungs. Am J Physiol Lung Cell Mol Physiol., 2022; 322(5): L699-L711.
    37 G Igawa, T Ai, T Yamamoto, K Ito, S Nojiri, K Saito, M Wakita, H Fukuda, S Hori, S Misawa, T Miida, K Seyama, K Takahashi, Y Tabe, T Naito. Antibody response and seroprevalence in healthcare workers after the BNT162b2 vaccination in a University Hospital at Tokyo. Sci Rep., 2022; 12(1): 8707.
    38 M Torasawa, T Yoshida, S Yagishita, Y Shimoda, M Shirasawa, Y Matsumoto, K Masuda, Y Shinno, Y Okuma, Y Goto, H Horinouchi, N Yamamoto, K Takahashi, Y Ohe. Nivolumab versus pembrolizumab in previously-treated advanced non-small cell lung cancer patients: A propensity-matched real-world analysis. Lung Cancer., 2022; 167: 49-57.
    39 K Tsuchiya, Y Hosaka, T Takahashi, M Chonan, Y Makita, I Katayama, T Ai, M Idei, Y Horiuchi,  K Yamatani, M Wakita, S Misawa, A Okuzawa, T Miida, T Naito, K Takahashi, Y Tabe. Meals and Room Temperature Storage do not Significantly Affect Feasibility of Direct RT-PCR Tests for SARS-CoV-2 Using Saliva. Clin Lab., 2022; 68(6). doi:10.7754/Clin.Lab.2021.210451.
    40 Nanjo Y, Okuma T, Kuroda Y, Hayakawa E, Shibayama K, Akimoto T, Murashima R, Kanamori K, Tsutsumi T, Suzuki Y, Namba Y, Makino F, Nagashima O, Sasaki S, Takahashi K. Multiple Types of Taste Disorders among Patients with COVID-19. Intern Med., 2022; 61(14): 2127-2134.
    41 T Miyawaki, T Naito, K Doshita, H Kodama, M Mori, N Nishioka, Y Iida, E Miyawaki, N Mamesaya, H Kobayashi, S Omori, R Ko, K Wakuda, A Ono, H Kenmotsu, H Murakami, K Mori, H Harada, M Endo, K Takahashi, T Takahashi. Predicting the efficacy of first-line immunotherapy by combining cancer cachexia and tumor burden in advanced non-small cell lung cancer. Thorac Cancer., 2022; 13(14): 2064-2074.
    42 T Yoshida, T Nagaoka, Y Nagata, Y Suzuki, T Tsutsumi, S Kuriyama, J Watanabe, S Togo, F Takahashi, M Matsushita, Y Joki, H Konishi, S Nunomura, K Izuhara, SJ Conway, K Takahashi. Periostin-related progression of different types of experim;ental pulmonary hypertension: A role for M2 macrophage and FGF-2 signalling. Respirology.; 2022; 27(7): 529-538.
    43 H Namkoong, K Takahashi, Y Okada, et al. DOCK2 is involved in the host genetics and biology of severe COVID-19. Nature., 2022; 609(7928): 754-760.
    44 C Iwamura, K Hirahara, M Kiuchi, S Ikehara, K Azuma, T Shimada, S Kuriyama, S Ohki, E Yamamoto, Y Inaba, Y Shiko, A Aoki, K Kokubo, R Hirasawa, T Hishiya, K Tsuji, T Nagaoka, S Ishikawa, A Kojima, H Mito, R Hase, Y Kasahara, N Kuriyama, T Tsukamoto, S Nakamura, T Urushibara, S Kaneda, S Sakao, M Tobiume, Y Suzuki, M Tsujiwaki, T Kubo, T Hasegawa, H Nakase, O Nishida, K Takahashi, K Baba, Y Iizumi, T Okazaki, MY Kimura, I Yoshino, H Igari, H Nakajima, T Suzuki,  H Hanaoka, TA Nakada, Y Ikehara, K Yokote, T Nakayama. Elevated Myl9 reflects the Myl9-containing microthrombi in SARS-CoV-2-induced lung exudative vasculitis and predicts COVID-19 severity. Proc Natl Acad Sci U S A., 2022; 119(33): e2203437
    45 SQ Wang, K Takahashi, Y Okada, et al. The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force. Nat Commun., 2022; 13(1): 4830.
    46 M Komura, T Sato, H Yoshikawa, N Arano Nitta, Y Suzuki, K Koike, Y Kodama, K Seyama, K Takahashi. Propylene glycol, a component of electronic cigarette liquid, damages epithelial cells in human small airways. Respir Res., 2022; 23(1): 216.
    47 M Takahashi, T Ai, K Sinozuka, Y Baba, G Igawa, S Nojiri, T Yamamoto, M Yuri, S Takei, K Sait, Y Horiuchi, T Kanno, M Tobiume, A Khasawneh, FJ Paran, M Hiki, M Wakita, T Miida, T Suzuki, A Okuzawa, K Takahashi, T Naito, Y Tabe. Activation of SARS-CoV-2 neutralizing antibody is slower than elevation of spike-specific IgG, IgM, and nucleocapsid-specific IgG antibodies. Scientific reports., 2022; 12(1): 14909.
    48 B Heissig, Y Salama, R Iakoubov R, Vehreschil JJ, Rios R, Nogueira T, Vehreschild MJGT, Stecher M, Mori H,  Lanznaster J, Adachi E, Jakob C, Tabe Y, Ruethrich M, Borgmann S, Naito T, Wille K, Valenti S, Hower M, Hattori N, Rieg S, Nagaoka T, Jensen BE, Yotsuyanagi H, Hertenstein B, Ogawa H, Wyen C, Kominami E, Roemmele C, Takahashi S, Rupp J, Takahashi K, Hanses F, Hattori K. COVID-19 Severity and Thrombo-Inflammatory Response Linked to Ethnicity. Biomedicine., 2022; 10(10) :2549.
    49 K Kurokawa, Y Mitsuishi, N Shimada, Y Kawakami, K Miura, T Miyawaki, T Asao, R Ko, T Shukuya, R Shibayama, S Nojiri, K Takahashi. Association between the efficacy and immune-related adverse events of pembrolizumab and chemotherapy in non-small cell lung cancer patients: a retrospective study. BMC Cancer., 2022; 22(1): 1047.
    50 K Takamochi K, K Hara, T Hayashi, S Kohsaka, F Takahashi, Y Suehara, M Shimokawa, K Suzuki. Clinical relevance of PD-L2 expression in surgically resected lung adenocarcinoma. Lung Cancer., 2022; 168: 50-58.
    51 S Kishikawa, T Hayashi, T Saito, K Takamochi, K Sasa, Y Suehara, F Takahashi, N Sasahara, S Kohsaka, K Suzuki, T Yao. Distinct properties of pure and mixed-type high-grade fetal lung adenocarcinomas by genetic profiling and transcription factor expression. Virchows Archiv., 2022; 480(3): 609-619.
    52 S Otake, S Chubachi, H Namkoong, K Nakagawara, H Tanaka, H Lee, A Morita, T Fukushima, M Watase, T Kusumoto, K Masaki, H Kamata, M Ishii, N Hasegawa, N Harada, T Ueda, S Ueda, T Ishiguro, K Arimura, F Saito,  T Yoshiyama, Y Nakano, Y Mutoh, Y Suzuki, K Murakami, Y Okada, R Koike, Y Kitagawa, A Kimura, S Imoto, S Miyano, S Ogawa, T Kanai, K Fukunaga, Japan C-TF. Clinical clustering with prognostic implications in Japanese COVID-19 patients: report from Japan COVID-19 Task Force, a nation-wide consortium to investigate COVID-19 host genetics. BMC Infect Dis., 2022; 22(1): 735.
    53 R Hatano, T Itoh, H Otsuka, H Saeki, A Yamamoto, D Song, Y Shirakawa, S Iyama, T Sato, N Iwao, N Harada, TM Aune, NH Dang, Y Kaneko, T Yamada, C Morimoto, K Ohnuma. Humanized anti-IL-26 monoclonal antibody as a novel targeted therapy for chronic graft-versus-host. Am J Transplant., 2022; 22(12): 2804-2820.
    54 H Lee, S Chubachi, H Namkoong, H Tanaka, S Otake, K Nakagawara, A Morita, T Fukushima, M Watase, T Kusumoto, K Masaki, H Kamata, M Ishii, N Hasegawa, N Harada, T Ueda, S Ueda, T Ishiguro, K Arimura, F Saito, T Yoshiyama, Y Nakano, Y Mutoh, Y Suzuki, K Murakami, Y Okada, R Koike, Y Kitagawa, A Kimura, S Imoto, S Miyano, S Ogawa, T Kanai, K Fukunaga, Japan C-TF. Effects of mild obesity on outcomes in Japanese patients with COVID-19: a nationwide consortium to investigate COVID-19 host genetics. Nutr Diabetes., 2022; 12(1): 38.
    55 T Fukushima, S Chubachi, H Namkoong, S Otake, K Nakagawara, H Tanaka, H Lee, A Morita, M Watase, T Kusumoto, K Masaki, H Kamata, M Ishii, N Hasegawa, N Harada, T Ueda, S Ueda, T Ishiguro, K Arimura, F Saito, T Yoshiyam, Y Nakano, Y Mutoh, Y Suzuki, K Murakami, Y Okada, R Koike, Y Kitagawa, A Kimura, S Imoto, S Miyano, S Ogawa, T Kanai, K Fukunaga, Japan C-TF. U-shaped association between abnormal serum uric acid levels and COVID-19 severity: reports from the Japan COVID-19 Task Force. Int J Infect Dis. 2022;122:747-54.
    56 LP McGarvey, SS Birring, AH Morice, PV Dicpinigaitis, ID Pavord, J Schelfhout, AM Nguyen, Q Li, A Tzontcheva, B Iskold, SA Green, C Rosa, DR Muccino, JA Smith, COUGH-1 and COUGH-2 Investigators including(Harada N). Efficacy and safety of gefapixant, a P2X3 receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials. Lancet., 2022; 399(10328): 909-23.
    57 S Oizumi, K Takamura, T Harada, M Tachihara, N Morikawa, R Honda, S Watanabe, T Asao, M Kunisaki, T Fukuhara, R Noro, E Kikuchi, Y Tsutani, T Tenma, K Kobayashi, H Dosaka-Akita; North East Japan Study Group, Hokkaido Lung Cancer Clinical Study Group. Phase II study of carboplatin-paclitaxel alone or with bevacizumab in advanced sarcomatoid carcinoma of the lung: HOT1201/NEJ024. Int J Clin Oncol., 2022; 27(4): 676-683.
    58 T Asao, S Wtanabe, T Tanaka, S Morita, K Kobayashi. A phase II study of carboplatin and etoposide plus durvalumab for previously untreated extensive-stage small-cell lung cancer (ES-SCLC) patients with a poor performance status (PS): NEJ045A study protocol. BMC Cancer., 2022; 22: 1135.H
    59 H Terai, K Soejima, A Shimokawa, H Horinouchi, J Shimizu, T Hase, R Kanemaru, K Watanabe, K Ninomiya, N Aragane, N Yanagitani, Y Sakata, M Seike, D Fujimoto, M Kasajima, A Kubo, S Kusumoto, Y Oyamada, K Fujiwara, M Mori, M Hashimoto, M Shingyoji, M Kodani, J Sakamoto, T Agatsuma, K Kashiwabara, M Inomata, M Tachihara, K Tanaka, K Hayashihara, N Koyama, K Matsui, K Minato, D Jingu, H Sakashita, S Hara, T Naito, A Okada, M Tanahashi, Y Sato, K Asano, T Takeda, K Nakazawa, T Harada, K Shibata, T Kato, E Miyaoka, I Yoshino, A Gemma, T Mitsudomi. Real-World Data Analysis of Pembrolizumab Monotherapy for NSCLC Using Japanese Postmarketing All-Case Surveillance Data. JTO Clin Res Rep., 2022; 3(11): 100404
    60 A Yoshimura, T Yamada, M Serizawa, H Uehara, K Tanimura, Y Okuma, A Fukuda, S Watanabe, N Nishioka, T Takeda, Y Chihara, S Takemoto, T Harada, O Hiranuma, Y Shirai, T Shukuya, A Nishiyama, Y Goto, S  Shiotsu, K Kunimasa, K Morimoto, Y Katayama, K Suda, T Mitsudomi, S Yano, H Kenmotsu, T Takahashi, K Takayama. High levels of AXL expression in untreated EGFR-mutated non-small cell lung cancer negatively impacts the use of osimertinib. Cancer Sci., 2023 Feb;114(2):606-618.
    61 LTH Nguyen, J Zhang, XY Rima, X Wang, KJ Kwak, T Okimoto, J Amann, MJ Yoon, T Shukuya, CL Chiang,  N Walters, Y Ma, D Belcher, H Li, AF Palmer, DP Carbone, LJ Lee, E Reátegui. An immunogold single extracellular vesicular RNA and protein (Au SERP) biochip to predict responses to immunotherapy in non-small cell lung cancer patients. J Extracell Vesicles., 2022; 11(9): e12258.
    62 K Hotta, T Hida, H Nokihara, M Morise, YH Kim, K Azuma, T Seto, Y Takiguchi, M Nishio, H Yoshioka, T Kumagai, S Watanabe, K Goto, M Satouchi, T Kozuki, T Shukuya,K Nakagawa, T Mitsudomi, N Yamamoto, T Asakawa, T Yoshimoto, S Takata, T Tamura. Final overall survival analysis from the phase III J-ALEX study of alectinib versus crizotinib in ALK inhibitor-naïve Japanese patients with ALK-positive non-small-cell lung cancer. ESMO Open., 2022; 7(4): 100527.
    63 C Zhang, C Wang, Z Yang, Y Bai, T Shukuya, ME Poh, S Ekman, J Li, Y Xu, S Deng. Identification of GPX4 as a therapeutic target for lung adenocarcinoma after EGFR-TKI resistance. Transl Lung Cancer Res., 2022; 11(5): 786-801.
    64 H Kenmotsu, K Wakuda, K Mori, T Kato, S Sugawara, K Kirita, Y Yoneshima, K Azuma, K Nishino, S Teraoka,  T Shukuya, K Masuda, H Hayashi, R Toyozawa, S Miura, D Fujimoto, K Nakagawa, N Yamamoto, T Takahashi.  Randomized Phase 2 Study of Osimertinib Plus Bevacizumab Versus Osimertinib for Untreated Patients With Nonsquamous NSCLC Harboring EGFR Mutations: WJOG9717L Study. J Thorac Oncol., 2022; 17(9): 1098-1108.
    65 T Shukuya, K Takamochi, H Sakurai, K Yoh, T Hishida, M Tsuboi, Y Goto, Y Kudo, Y Ohde, S Okumura, M Taguri, H Kunitoh. Efficacy of Adjuvant Chemotherapy With Tegafur-Uracil in Patients With Completely Resected, Node-Negative NSCLC-Real-World Data in the Era of Molecularly Targeted Agents and Immunotherapy. JTO Clin Res Rep., 2022; 3(5):100320.
    66 Y Ozawa, N Yamamoto, K Yamamoto, K Ito, H Kenmotsu, H Hayashi, T Shukuya, D Fujimoto, S Sugawara, S Niho, Y Ohe, H Okamoto, K Nakagawa, K Kiura, I Yoshino, A Gemma. Creation of an Integrated Clinical Trial Database and Data Sharing for Conducting New Research by the Japan Lung Cancer Society. JTO Clin Res Rep., 2022; 3(5): 100317.
    67 H Toei, X Zhang, K Seyama, D Yashiro, Y Kuwatsuru, R Kuwatsuru. Prophylactic renal artery embolization before pregnancy in patients with lymphangioleiomyomatosis and renal angiomyolipoma. J Int Med Res., 2022; 50(9): 3000605221123897.
    68 K Seyama, M Suzuki, S Tasaka, T Nukiwa, T Sato, S Konno, S Sorrells, J Chen, ME Aragonés, H Minamino. Long-term safety of Prolastin®-C, an alpha1-proteinase inhibitor, in Japanese patients with alpha1-antitrypsin deficiency. Respir Investig., 2022; 60: 831-839.
    69 C Inoue, Y Miki, Saito-Koyama R, Kobayashi K, Seyama K, Okada Y, Sasano H. Vasohibin-1 and -2 in pulmonary lymphangioleiomyomatosis (LAM) cells associated with angiogenic and prognostic factors. Pathol Res Pract., 2022;230:153758.
    70 M Saita, Y Yan, K Ito, H Sasano, K Seyama, T Naito. Reactogenicity following two doses of the BNT162b2 mRNA COVID-19 vaccine: Real-world evidence from healthcare workers in Japan. J Infect Chemother., 2022; 28:116-119.
    71 Suda M, Paul K, Minamino T, Tchkoni T, Kirkland JL. Cellular Senescence and the Endocrine System. Endocr Rev. (in press)
    72 Hayashi Y, Shimizu I, Yoshida Y, Ikegami R, Suda M, Katsuumi G, Fujiki S, Ozaki K, Abe M, Sakimura K, Okuda S, Hayano T, Nakamura K, Walsh K, Jespersen N, Nielsen S, Scheele C, Minamino T. Coagulation factors promote brown adipose tissue dysfunction and abnormal systemic metabolism in obesity. iScience 2022; 25(7): 104547. doi: 10.1016/j.isci.2022.104547
    73 Fujiki S, Tanaka A, Imai T, Shimabukuro M, Uehara H, Nakamura I, Matsunaga K, Suzuki M, Kashimura T, Minamino T, Inomata T, Node K; CANDLE Trial Investigators. Body fluid regulation via chronic inhibition of sodium-glucose cotransporter-2 in patients with heart failure: a post hoc analysis of the CANDLE trial. Clin Res Cardiol. 2022 Jun 22. doi: 10.1007/s00392-022-02049-4
    74 Ikami Y, Izumi D, Hasegawa Y, Suzuki N, Sakaguchi Y, Hakamata T, Otsuki S, Yagihara N, Iijima K, Kashimura T, Chinushi M, Minamino T, Inomata T. The Risk of Ventricular Tachyarrhythmias in Patients with Antimitochondrial Antibodies-Related Noncardiac Diseases. Int Heart J. 2022; 63(3): 476-485. doi: 10.1536/ihj.22-075.
    75 P Park N, Marquez J, Pham TK, Ko TH, Youm JB, Kim M, Choi SH, Moon J, Flores J, Ko KS, Rhee BD, Shimizu I, Minamino T, Du Ha J, Hwang JY, Yang SJ, Park CS, Kim HK, Han J. Cereblon contributes to cardiac dysfunction by degrading Cav1.2α. Eur Heart J. 2022 May 21;43(20):1973-1989. doi: 10.1093/eurheartj/ehac072.
    76 Tamiya E, Yamashita H, Takabe T, Matsumoto T, Kajihara J, Yamamoto S, Kanoh T, Koide H, Minamino T. Evaluation of the Effect of Topiroxostat on Renal Function in Patients with Hyperuricemia: STOP-C Study, a Retrospective Observational Cohort Study. Drugs Real World Outcomes. 2022 Jun;9(2):299-306. doi: 10.1007/s40801-022-00291-w.
    77 Minamino T. Greetings from the new Editor-in-Chief. J Cardiol. 2023 Jan;81(1):2. doi: 10.1016/j.jjcc.2022.11.004
    78 Ishii J, Kashiwabara K, Ozaki Y, Takahashi H, Kitagawa F, Nishimura H, Ishii H, Iimuro S, Kawai H, Muramatsu T, Naruse H, Iwata H, Tanizawa-Motoyama S, Ito H, Watanabe E, Matsuyama Y, Fukumoto Y, Sakuma I, Nakagawa Y, Hibi K, Hiro T, Hokimoto S, Miyauchi K, Ohtsu H, Izawa H, Ogawa H, Daida H, Shimokawa H, Saito Y, Kimura T, Matsuzaki M, Nagai R. Small Dense Low-Density Lipoprotein Cholesterol and Cardiovascular Risk in Statin-Treated Patients with Coronary Artery Disease. J Atheroscler Thromb. 2022 Oct 1;29(10):1458-1474
    79 Iwata H, Minamino T. Identification of a novel therapeutic target in vascular dysfunction: a showcase of reverse and forward translational research linking bench to bedside. Eur Heart J. 2022 Feb 10;43(6):501-503.
    80 Moriya S, Wada H, Iwata H, Endo H, Doi S, Ogita M, Dohi T, Okazaki S, Suwa S, Miyauchi K, Daida H, Minamino T. Red Cell Distribution Width Predicts Long-Term Cardiovascular Outcomes in Patients with Chronic Coronary Syndrome. Int Heart J. 2022;63(6):1041-1047
    81 Fukase T, Dohi T, Koike T, Yasuda H, Takeuchi M, Takahashi N, Chikata Y, Endo H, Doi S, Nishiyama H, Okai I, Iwata H, Okazaki S, Miyauchi K, Daida H, Minamino T. Long-term impact of β-blocker in elderly patients without myocardial infarction after percutaneous coronary intervention. ESC Heart Fail. 2022 Feb;9(1):545-554.
    82 Takeuchi M, Dohi T, Fukase T, Nishio R, Takahashi N, Endo H, Doi S, Kato Y, Okai I, Iwata H, Okazaki S, Isoda K, Miyauchi K, Minamino T. Comparison of clinical outcomes between percutaneous coronary intervention for de novo lesions versus in-stent restenosis lesions. Cardiovasc Interv Ther. 2022 Apr;37(2):324-332.
    83 Sakuma M, Iimuro S, Shinozaki T, Kimura T, Nakagawa Y, Ozaki Y, Iwata H, Miyauchi K, Daida H, Suwa S, Sakuma I, Nishihata Y, Saito Y, Ogawa H, Matsuzaki M, Ohashi Y, Taguchi I, Toyoda S, Inoue T, Nagai R. Optimal target of LDL cholesterol level for statin treatment: challenges to monotonic relationship with cardiovascular events. BMC Med. 2022 Nov 14;20(1):441
    84 Fukase T, Dohi T, Nishio R, Takeuchi M, Takahashi N, Chikata Y, Endo H, Doi S, Nishiyama H, Okai I, Iwata H, Okazaki S, Miyauchi K, Daida H, Minamino T. Combined impacts of low apolipoprotein A-I levels and reduced renal function on long-term prognosis in patients with coronary artery disease undergoing percutaneous coronary intervention. Clin Chim Acta. 2022 Nov 1;536:180-190.
    85 Chikata Y, Iwata H, Miyosawa K, Koike T, Yasuda H, Funamizu T, Doi S, Endo H, Wada H, Naito R, Ogita M, Dohi T, Kasai T, Isoda K, Okazaki S, Miyauchi K, Minamino T. Dipeptidyl peptidase-4 inhibitors reduced long-term cardiovascular risk in diabetic patients after percutaneous coronary intervention via insulin-like growth factor-1 axis. Sci Rep. 2022 Mar 24;12(1):5129.
    86 Funamizu T, Iwata H, Chikata Y, Doi S, Endo H, Wada H, Naito R, Ogita M, Kato Y, Okai I, Dohi T, Kasai T, Isoda K, Okazaki S, Miyauchi K, Minamino T. A Prognostic Merit of Statins in Patients with Chronic Hemodialysis after Percutaneous Coronary Intervention-A 10-Year Follow-Up Study. J Clin Med. 2022 Jan 13;11(2):390.
    87 Fukase T, Dohi T, Nishio R, Takeuchi M, Takahashi N, Chikata Y, Endo H, Doi S, Nishiyama H, Okai I, Iwata H, Okazaki S, Miyauchi K, Daida H, Minamino T. Paradoxical Long-Term Impact Between Serum Apolipoprotein E and High-Density Lipoprotein Cholesterol in Patients Undergoing Percutaneous Coronary Intervention. J Atheroscler Thromb. 2022 Aug 5.
    88 Nishiyama H, Funamizu T, Iwata H, Endo H, Chikata Y, Doi S, Wada H, Naito R, Ogita M, Kato Y, Okai I, Dohi T, Kasai T, Isoda K, Okazaki S, Miyauchi K, Minamino T. Low apolipoprotein A1 was associated with increased risk of cancer mortality in patients following percutaneous coronary intervention: A 10-year follow-up study. Int J Cancer. 2022 Nov 1;151(9):1482-1490.
    89 Toyota T, Morimoto T, Iimuro S, Fujita R, Iwata H, Miyauchi K, Inoue T, Nakagawa Y, Nishihata Y, Daida H, Ozaki Y, Suwa S, Sakuma I, Furukawa Y, Shiomi H, Watanabe H, Yamaji K, Saito N, Natsuaki M, Ohashi Y, Matsuzaki M, Nagai R, Kimura T. Low-Density Lipoprotein Cholesterol Levels on Statins and Cardiovascular Event Risk in Stable Coronary Artery Disease - An Observation From the REAL-CAD Study. Circ J. 2022 Sep 14
    90 Nishio R, Dohi T, Takeuchi M, Takahashi N, Endo H, Doi S, Okai I, Iwata H, Okazaki S, Miyauchi K, Daida H, Minamino T. Combined impact of residual inflammatory risk and chronic kidney disease on long-term clinical outcomes in patients undergoing percutaneous coronary intervention. J Cardiol. 2022 Apr;79(4):509-514.
    91 Natsuaki M, Morimoto T, Iimuro S, Fujita R, Iwata H, Miyauchi K, Inoue T, Nakagawa Y, Nishihata Y, Daida H, Ozaki Y, Suwa S, Sakuma I, Furukawa Y, Shiomi H, Watanabe H, Yamaji K, Saito N, Matsuzaki M, Nagai R, Kimura T; REAL-CAD Investigators. Thrombotic Risk Stratification and Intensive Statin Therapy for Secondary Prevention of Coronary Artery Disease - Insights From the REAL-CAD Study. Circ J. 2022 Aug 25;86(9):1416-1427.
    92 Iwata A, Sano Y, Wanaka H, Kobayashi S, Okamoto K, Yamahara J, Inaba M, Konishi Y, Inoue J, Kanayama A, Yamamoto S, Iwata H. Maximum knee extension velocity without external load is a stronger determinant of gait function than quadriceps strength in the early postoperative period following total knee arthroplasty. PLoS One. 2022 Nov 22;17(11):e0276219.
    93 Takeuchi M, Dohi T, Matsumura M, Fukase T, Nishio R, Takahashi N, Endo H, Nishiyama H, Doi S, Okai I, Iwata H, Okazaki S, Miyauchi K, Daida H, Minamino T. Relationship Between Optical Coherence Tomography-Derived In-Stent Neoatherosclerosis and the Extent of Lipid-Rich Neointima by Near-Infrared Spectroscopy and Intravascular Ultrasound: A Multimodal Imaging Study. J Am Heart Assoc. 2022 Dec 6;11(23):e026569.
    94 Omote K, Yokota I, Nagai T, Sakuma I, Nakagawa Y, Kamiya K, Iwata H, Miyauchi K, Ozaki Y, Hibi K, Hiro T, Fukumoto Y, Mori H, Hokimoto S, Ohashi Y, Ohtsu H, Ogawa H, Daida H, Iimuro S, Shimokawa H, Saito Y, Kimura T, Matsuzaki M, Nagai R, Anzai T. High-Density Lipoprotein Cholesterol and Cardiovascular Events in Patients with Stable Coronary Artery Disease Treated with Statins: An Observation from the REAL-CAD Study. J Atheroscler Thromb. 2022 Jan 1;29(1):50-68.
    95 Takamochi K, Suzuki K, Tsuboi M, Niho S, Ishikura S, Oyamada S, Yamaguchi T, Okada M; Advanced Clinical Trial Chest Surgery Group. Randomized phase II trial of pemetrexed-cisplatin plus bevacizumab or thoracic radiotherapy followed by surgery for stage IIIA (N2) nonsquamous non-small cell lung cancer. J Thorac Cardiovasc Surg. 2022 Sep;164(3):661-671.e4.
    96 Nishizaki Y, Miyauchi K, Iwata H, Inoue T, Hirayama A, Kimura K, Ozaki Y, Murohara T, Ueshima K, Kuwabara Y, Tanaka-Mizuno S, Yanagisawa N, Sato T, Daida H. Study protocol and baseline characteristics of Randomized trial for Evaluation in Secondary Prevention Efficacy of Combination Therapy-Statin and Eicosapentaenoic Acid: RESPECT-EPA, the combination of a randomized control trial and an observational biomarker study. Am Heart J. 2022 Nov 11;257:1-8
    97 Nishio R, Dohi T, Fukase T, Takeuchi M, Takahashi N, Endo H, Doi S, Okai I, Iwata H, Okazaki S, Miyauchi K, Daida H, Minamino T. Impact of simple equation for estimating appendicular skeletal muscle mass in patients with stable coronary artery disease undergoing percutaneous coronary intervention. Int J Cardiol Heart Vasc. 2022 Dec 12;44:101163
    98 Nozaki YO, Fujimoto S, Kawaguchi YO, Aoshima C, Kamo Y, Sato H, Kudo H, Takamura K, Kudo A, Takahashi D, Hiki M, Dohi T, Tomizawa N, Kumamaru KK, Aoki S, Minamino T. Prognostic value of the optimal measurement location of on-site CT-derived fractional flow reserve. J Cardiol. 2022 Jul;80(1):14-21
    99 Sonoda T, Wada H, Ogita M, Takahashi D, Nishio R, Yasuda K, Takeuchi M, Yatsu S, Shitara J, Tsuboi S, Dohi T, Suwa S, Miyauchi K, Minamino T. Clinical features and predictors of outcome in patients with acute myocardial infarction complicated by out-of-hospital cardiac arrest. BMC Cardiovasc Disord. 2022 Apr 19;22(1):185.
    100 Yamamoto MH, Kondo S, Mizukami T, Yasuhara S, Wakabayashi K, Kobayashi N, Sambe T, Hibi K, Nanasato M, Sugiyama T, Kakuta T, Kondo T, Mitomo S, Nakamura S, Takano M, Yonetsu T, Ashikaga T, Dohi T, Yamamoto H, Kozuma K, Yamashita J, Yamaguchi J, Ohira H, Mitsumata K, Namiki A, Kimura S, Honye J, Kotoku N, Higuma T, Natsumeda M, Ikari Y, Sekimoto T, Mori H, Suzuki H, Otake H, Isomura N, Ochiai M, Suwa S, Shinke T; TACTICS investigators. Rationale and design of the TACTICS registry: Optical coherence tomography guided primary percutaneous coronary intervention for patients with acute coronary syndrome. J Cardiol. 2022 Dec;80(6):505-510. doi: 10.
    101 Takahashi D, Wada H, Ogita M, Yasuda K, Nishio R, Takeuchi M, Shitara J, Tsuboi S, Dohi T, Suwa S, Miyauchi K, Daida H, Minamino T. Impact of Lipoprotein(a) as a Residual Risk Factor in Long-Term Cardiovascular Outcomes in Patients With Acute Coronary Syndrome Treated With Statins. Am J Cardiol. 2022 Apr 1;168:11-16
    102 Naito R, Kasai T, Dohi T, Takaya H, Narui K, Momomura SI. Factors Associated With the Improvement of Left Ventricular Systolic Function by Continuous Positive Airway Pressure Therapy in Patients With Heart Failure With Reduced Ejection Fraction and Obstructive Sleep Apnea. Front Neurol. 2022 Mar 10;13:781054.
    103 Tomizawa N, Nozaki Y, Fujimoto S, Fan R, Takahashi D, Kudo A, Kamo Y, Aoshima C, Kawaguchi Y, Takamura K, Hiki M, Dohi T, Okazaki S, Kumamaru KK, Minamino T, Aoki S. Feasibility of CT Angiography-derived Kinetic Energy of Coronary Flow to Improve the Detection of Hemodynamically Significant Coronary Stenosis. Radiol Cardiothorac Imaging. 2022 Dec 15;4(6):e220147.
    104 Yasuda H, Isoda K, Okazaki S, Minamino T. Capture of Part of a Vessel Wall by a Coronary Orbital Atherectomy System. CJC Open. 2022 Sep 29;4(11):994-995.
    105 Kojima Y, Higuchi R, Hagiya K, Saji M, Takamisawa I, Iguchi N, Takanashi S, Doi S, Okazaki S, Sato K, Tamura H, Takayama M, Ikeda T, Isobe M. Prognosis of patients with active cancer undergoing transcatheter aortic valve implantation: An insight from Japanese multicenter registry. Int J Cardiol Heart Vasc. 2022 May 2;40:101045.
    106 Kida K, Nishitani-Yokoyama M, Kono Y, Kamiya K, Kishi T, Node K, Makita S, Kimura Y, Ishihara S, for the Japanese Association of Cardiac Rehabilitation (JACR) Public Relations Committee. Second Nationwide Survey of Japanese Cardiac Rehabilitation Training Facilities During the Coronavirus Disease 2019 (COVID-19) Outbreak. Circ Rep. 2022. 4(10):469-473.
    107 Honzawa A, Nishitani-Yokoyama M*, Shimada K, Kunimoto M, Matsubara T, Matsumori R, Kasuya H, Fujiwara K, Doi M, Takagi-Kawahara K, Abulimiti A, Xu J, Shimada A, Yamamoto T, Amano A, Asai T, Daida H, Minamino T. Effects of Phase II Cardiac Rehabilitation on Physical Function and Anxiety Levels in Frail Patients. Circ Rep. 2022.4(7):308-314.
    108 Saitoh M, Takahashi T, Morisawa T, Honzawa A, Yokoyama M, Abulimiti A, Kagiyama N, Kasai T, Minamino T, Asai T, Fujiwara T, Daida H. Remote Cardiac Rehabilitation in Older Cardiac Disease: A Randomized Case Series Feasibility Study. Cardiol Res. 2022.13(1):57-64.
    109 Shigeru Makita, Takanori Yasu, Yoshihiro J Akashi, Hitoshi Adachi, Hideo Izawa, Shunichi Ishihara, Yoshitaka Iso, Hideo Ohuchi, Kazuto Omiya, Yusuke Ohya, Koichi Okita, Yutaka Kimura, Akira Koike, Masahiro Kohzuki, Shinji Koba, Masataka Sata, Kazunori Shimada, Tomoki Shimokawa, Hirokazu Shiraishi, Naokata Sumitomo, Tetsuya Takahashi, Tomoyuki Takura, Hiroyuki Tsutsui, Masatoshi Nagayama, Emiko Hasegawa, Yoshihiro Fukumoto, Yutaka Furukawa, Shin-ichiro Miura, Satoshi Yasuda, Sumio Yamada, Yuichiro Yamada, Dai Yumino, Toshiko Yoshida, Takuji Adachi, Toshimi Ikegame, Kazuhiro P Izawa, Takeshi Ishida, Neiko Ozasa, Naohiko Osada, Hiroaki Obata, Naoya Kakutani, Yusuke Kasahara, Masaaki Kato, Kentaro Kamiya, Shintaro Kinugawa, Yuji Kono, Yasuyuki Kobayashi, Teruyuki Koyama, Kazuhiro Sase, Shinji Sato, Tatsuhiro Shibata, Norio Suzuki, Daisuke Tamaki, Minako Yamaoka-Tojo, Michio Nakanishi, Eisaku Nakane, Mari Nishizaki, Taiki Higo, Kanta Fujimi, Tasuku Honda, Yasuharu Matsumoto, Noriko Matsumoto, Ikuko Miyawaki, Makoto Murata, Shusuke Yagi, Masanobu Yanase, Midori Yamada, Miho Yokoyama, Noboru Watanabe, Haruki Ito, Takeshi Kimura, Syunei Kyo, Yoichi Goto, Ryuji Nohara, Ken-Ichi Hirata, on behalf of the Japanese Circulation Society/the Japanese Association of Cardiac Rehabilitation Joint Working Group. JCS/JACR 2021 Guideline on Rehabilitation in Patients With Cardiovascular Disease. Circ J. 2023. 87. 155-235.
    110 Joki Y, Konishi H*, Takasu K, Minamino T. Tofogliflozin, a sodium-glucose cotransporter 2 inhibitor, improves pulmonary vascular remodeling due to left heart disease in mice. J Cardiol. 2022 Oct 13;S0914-5087(22)00256-8
    111 Yoshida T, Nagaoka T*, Nagata Y, Suzuki Y, Tsutsumi T, Kuriyama S, Watanabe J, Togo T, Takahashi F, Matsushita M, Joki Y, Konishi H, Nunomura S, Izuhara K, Simon J Conway, Takahashi K. Periostin-related progression of different types of experimental pulmonary hypertension: A role for M2 macrophage and FGF-2 signalling. Respirology. 2022 Mar 22
    112 Kaneko T, Kagiyama N, Nakamura Y, Hirasawa T, Murata A, Morimoto R, Miyazaki S, Minamino T. Effectiveness of real-time tele-ultrasound for echocardiography in resource-limited medical teams. J Echocardiogr. 2022 Mar;20(1):16-23
    113 Sasaki R, Kurebayashi N, Eguchi H, Horimoto Y, Shiga T, Miyazaki S, Kashiyama T, Akamatsu W, Saito M. Involvement of kallikrein-PAR2-proinflammatory pathway in severe trastuzumab-induced cardiotoxicity. Cancer Sci. 2022 Oct;113(10):3449-3462.
    114 Kosmala W, Negishi T, Thavendiranathan P, Penicka M, De Blois J, Murbræch K, Miyazaki S, Shirazi M, Santoro C, Vinereanu D, Cho GY, Hristova K, Popescu BA, Kurosawa K, Izumo M, Negishi K, Przewlocka-Kosmala M, Marwick TH. Incremental Value of Myocardial Work over Global Longitudinal Strain in the Surveillance for Cancer-Treatment-Related Cardiac Dysfunction: A Case-Control Study. J Clin Med. 2022 Feb 9;11(4):912.
    115 Negishi T, Thavendiranathan P, Penicka M, Lemieux J, Murbraech K, Miyazaki S, Shirazi M, Santoro C, Cho GY, Popescu BA, Kosmala W, Costello B, la Gerche A, Mottram P, Thomas L, Seldrum S, Hristova K, Bansal M, Kurosawa K, Fukuda N, Yamada H, Izumo M, Tajiri K, Sinski M, Vinereanu D, Shkolnik E, Banchs J, Kutty S, Negishi K, Marwick TH. Cardioprotection Using Strain-Guided Management of Potentially Cardiotoxic Cancer Therapy: 3-Year Results of the SUCCOUR Trial. JACC Cardiovasc Imaging. 2022 Nov 16:S1936-878X(22)00616-7
    116 Miyazaki S, Miyauchi K, Hayashi H, Yamashiro K, Tanaka R, Nishizaki Y, Nojiri S, Suwa S, Sumiyoshi M, Nakazato Y, Urabe T, Hattori N, Minamino T, Daida H. Trends of anticoagulant use and outcomes of patients with non-valvular atrial fibrillation: Findings from the RAFFINE registry. J Cardiol. 2022 Jul;80(1):41-48
    117 Yamashiro K, Tanaka R, Miyazaki S, Miyauchi K, Hayashi H, Nishizaki Y, Nojiri S, Suwa S, Sumiyosi M, Nakazato Y, Urabe T, Hattori N, Minamino T, Daida H. Comparison of primary and secondary stroke prevention in patients with nonvalvular atrial fibrillation: Results from the RAFFINE registry. J Stroke Cerebrovasc Dis. 2022 Dec;31(12):106871.
    118 Murata A, Kagiyama N, Miyazaki S, Kaneko T, Shimada N, Mitsuishi Y, Minamino T. Severe Aortic Regurgitation by Nonbacterial Thrombotic Endocarditis Treated with Anticoagulation Therapy. CASE (Phila). 2022 May 20;6(5):205-208.
    119 Ohtsu H, Shimomura A, Miyazaki S, Yonemoto N, Ueda S, Shimizu C, Sase K. Cardiotoxicity of adjuvant chemotherapy with trastuzumab: a Japanese claim-based data analysis. Open Heart. 2022 Aug;9(2):e002053.
    120 Kaneko T, Miyazaki S, Koike T, Murata A, Morimoto R, Hirose K, Takamura K, Endo D, Amano A, Minamino T. Atypical Shone’s Complex Diagnosed at 70 Years Old: Presenting with Double-orifice Mitral Valve, Bicuspid Aortic Valve, and Aortic Coarctation. Intern Med. 2022 May 1;61(9):1367-1370
    121 Morimoto Y, Takahashi T, Sawa R, Saitoh M, Morisawa T, Kagiyama N, Kasai T, Dinesen B, Hollingdal M, Refsgaard J, Daida H. Web Portals for Patients With Chronic Diseases: Scoping Review of the Functional Features and Theoretical Frameworks of Telerehabilitation Platforms. J Med Internet Res. 2022 Jan 27;24(1):e27759.
    122 Yamamoto S, Yamasaki S, Higuchi S, Kamiya K, Saito H, Saito K, Ogasahara Y, Maekawa E, Konishi M, Kitai T, Iwata K, Jujo K, Wada H, Kasai T, Nagamatsu H, Ozawa T, Izawa K, Aizawa N, Makino A, Oka K, Momomura SI, Kagiyama N, Matsue Y. Prevalence and prognostic impact of cognitive frailty in elderly patients with heart failure: sub-analysis of FRAGILE-HF. ESC Heart Fail. 2022 Jun;9(3):1574-1583
    123 Sawa R, Saitoh M, Morisawa T, Takahashi T, Morimoto Y, Kagiyama N, Kasai T, Dinesen B, Daida H. The Potential Application of Commercially Available Active Video Games to Cardiac Rehabilitation: Scoping Review. JMIR Serious Games. 2022 Mar 18;10(1):e31974.
    124 Nogi K, Ueda T, Matsue Y, Nogi M, Ishihara S, Nakada Y, Kawakami R, Kagiyama N, Kitai T, Oishi S, Akiyama E, Suzuki S, Yamamoto M, Kida K, Okumura T, Saito Y. Effect of carperitide on the 1 year prognosis of patients with acute decompensated heart failure. ESC Heart Fail. 2022 Apr;9(2):1061-1070.
    125 Maeda D, Matsue Y, Kagiyama N, Jujo K, Saito K, Kamiya K, Saito H, Ogasahara Y, Maekawa E, Konishi M, Kitai T, Iwata K, Wada H, Hiki M, Dotare T, Sunayama T, Kasai T, Nagamatsu H, Ozawa T, Izawa K, Yamamoto S, Aizawa N, Yonezawa R, Oka K, Momomura SI, Minamino T. Inaccurate recognition of own comorbidities is associated with poor prognosis in elderly patients with heart failure. ESC Heart Fail. 2022 Apr;9(2):1351-1359
    126 Kagiyama N, Komatsu T, Nishikawa M, Hiki M, Kobayashi M, Matsuzawa W, Daida H, Minamino T, Naito T, Sugita M, Miyazaki K, Anan H, Kasai T. Impact of a telemedicine system on work burden and mental health of healthcare providers working with COVID-19: a multicenter pre-post prospective study. JAMIA Open. 2022 May 20;5(2):ooac037.
    127 Saito H, Matsue Y, Kamiya K, Kagiyama N, Maeda D, Endo Y, Ueno H, Yoshioka K, Mizukami A, Saito K, Ogasahara Y, Maekawa E, Konishi M, Kitai T, Iwata K, Jujo K, Wada H, Hiki M, Dotare T, Sunayama T, Kasai T, Nagamatsu H, Ozawa T, Izawa K, Yamamoto S, Aizawa N, Wakaume K, Oka K, Momomura SI, Minamino T. Sarcopenic obesity is associated with impaired physical function and mortality in older patients with heart failure: insight from FRAGILE-HF. BMC Geriatr. 2022 Jul 5;22(1):556.
    128 Ito M, Maeda D, Matsue Y, Shiraishi Y, Dotare T, Sunayama T, Nogi K, Takei M, Ueda T, Nogi M, Ishihara S, Nakada Y, Kawakami R, Kagiyama N, Kitai T, Oishi S, Akiyama E, Suzuki S, Yamamoto M, Kida K, Okumura T, Nagatomo Y, Kohno T, Nakano S, Kohsaka S, Yoshikawa T, Saito Y, Minamino T. Association between class of foundational medication for heart failure and prognosis in heart failure with reduced/mildly reduced ejection fraction. Sci Rep. 2022 Oct 5;12(1):16611.
    129 Patel HB, Yanamala N, Patel B, Raina S, Farjo PD, Sunkara S, Tokodi M, Kagiyama N, Casaclang-Verzosa G, Sengupta PP. Electrocardiogram-Based Machine Learning Emulator Model for Predicting Novel Echocardiography-Derived Phenogroups for Cardiac Risk-Stratification: A Prospective Multicenter Cohort Study. J Patient Cent Res Rev. 2022 Apr 18;9(2):98-107.
    130 Sunayama T, Maeda D, Matsue Y, Kagiyama N, Jujo K, Saito K, Kamiya K, Saito H, Ogasawara Y, Maekawa E, Konishi M, Kitai T, Iwata K, Wada H, Hiki M, Dotare T, Kasai T, Nagamatsu H, Ozawa T, Izawa K, Yamamoto S, Aizawa N, Yonezawa R, Oka K, Momomura SI, Minamino T. Prognostic value of postural hypotension in hospitalized patients with heart failure. Sci Rep. 2022 Feb 18;12(1):2802.
    131 Kagiyama N, Maekawara S, Izumi Y, Watanabe N, Otsuji Y, Yoshida K. Dynamic Nature of the Mitral Valve Morphology: Consideration of the Normal Ranges. J Am Soc Echocardiogr. 2022 Sep 16:S0894-7317(22)00459-X.
    132 Dotare T, Maeda D, Matsue Y, Sunayama T, Kida K, Kitai T, Kagiyama N, Yamaguchi T, Okumura T, Mizuno A, Oishi S, Inuzuka Y, Akiyama E, Suzuki S, Yamamoto M, Minamino T. Early drop in systolic blood pressure is associated with poor diuretic response and prognosis in patients with acute heart failure. Eur Heart J Acute Cardiovasc Care. 2022 Nov 2;11(10):749-757.
    133 Kagiyama N, Tokodi M, Sengupta PP. Machine Learning in Cardiovascular Imaging. Heart Fail Clin. 2022 Apr;18(2):245-258.
    134 Matsubara T, Sumiyoshi M, Kimura A, Minami-Takano A, Maruyama K, Kimura Y, Tabuchi H, Hayashi H, Odagiri F, Sekita G, Tokano T, Nakazato Y, Nakata Y, Minamino T. Trend in Age at the Initial Pacemaker Implantation in Patients With Bradyarrhythmia - A 50-Year Analysis (1970-2019) in Japan. Circ J. 2022 Jul 25;86(8):1292-1297. doi: 10.1253/circj.CJ-21-0947. Epub 2022 Mar 31.PMID: 35354715
    135 K Ishii, Y Matsue, K Miyauchi, S Miyazaki, H Hidemori, Y Nishizaki, S Nojiri, Y Saito, K Nagashima, Y Okumura, H Daida, T Minamino.  Predicting new-onset heart failure hospitalization of patients with atrial fibrillation: development and external validations of a risk score                                                      European Heart Journal – Quality of Care and Clinical Outcomes. Dec 2022, qcac085
    136 Takamura K, Fujimoto S, Mita T, Kawaguchi YO, Kurita M, Kadowaki S, Kamo Y, Aoshima C, Nozaki YO, Takahashi D, Kudo A, Hiki M, Tomizawa N, Ikeda F, Satoh H, Watada H, Minamino T. Identification of Risk Factors for Coronary Artery Disease in Asymptomatic Patients with Type 2 Diabetes MellitusJ Clin Med. 2022;1:1226
    137 Aoshima C, Fujimoto S, Kudo A, Kawaguchi YO, Takamura K, Matsue Y, Kato T, Kawamura Y, Kimura S, Kamo Y, Nozaki YO, Takahashi D, Tomizawa N, Hiki M, Kasai T, Nojiri S, Miyauchi H, Hirano KI, Shimada K, Murakami K, Minamino T. Clinical significance of 123 I-BMIPP washout rate in patients with uncertain chronic heart failure. Eur J Nucl Med Mol Imaging. 2022;49:3129-3139
    138 Einstein AJ, Hirschfeld C, Williams MC, Vitola JV, Better N, Villines TC, Cerci R, Shaw LJ, Choi AD, Dorbala S, Karthikeyan G, Lu B, Sinitsyn V, Ansheles AA, Kudo T, Bucciarelli-Ducci C, Nørgaard BL, Maurovich-Horvat P, Campisi R, Milan E, Louw L, Allam AH, Bhatia M, Sewanan L, Malkovskiy E, Cohen Y, Randazzo M, Narula J, Morozova O, Pascual TNB, Pynda Y, Dondi M, Paez D; INCAPS COVID 2 Investigators Group. Worldwide Disparities in Recovery of Cardiac Testing 1 Year Into COVID-19. J Am Coll Cardiol. 2022;79:2001-2017
    139 Inage H, Tomizawa N, Otsuka Y, Aoshima C, Kawaguchi Y, Takamura K, Matsumori R, Kamo Y, Nozaki Y, Takahashi D, Kudo A, Hiki M, Kogure Y, Fujimoto S, Minamino T, Aoki S. Use of a deep-learning-based lumen extraction method to detect significant stenosis on coronary computed tomography angiography in patients with severe coronary calcification. Egypt Heart J. 2022 ;74:43.
    140 Tomizawa N, Nozaki Y, Fujimoto S, Takahashi D, Kudo A, Kamo Y, Aoshima C, Kawaguchi Y, Takamura K, Hiki M, Dohi T, Okazaki S, Kumamaru KK, Minamino T, Aoki S. Coronary flow disturbance assessed by vorticity as a cause of functionally significant stenosis. Eur Radiol. 2022;32:6859-6867
    141 Miyauchi H, Hirano K, Nakano Y, Shimada K, Nishikawa M, Yamamoto H, Nakamura A, Miyake A, Aoshima C, Fujimoto S, Nakatani D, Yamada T, Amamno T, Nakajima K. 123I-BMIPP Scintigraphy Shows That CNT-01 (Tricaprin) Improves Myocardial Lipolysis in Patients with Idiopathic Triglyceride Deposit Cardiomyovasculopathy: First Randomized Controlled, Exploratory Trial for TGCV. Ann Nucl Cardiol 2022; 8: 67-75.
    142 Sato H, Fujimoto S, Kawaguchi YO, Nozaki YO, Tomizawa N, Kogure Y, Minamino T. Dual-energy CT imaging of atherosclerotic plaque using novel ultrasmall superparamagnetic iron oxide in hyperlipidemic rabbits. Acta Radiol. 2022 in press
    143 Misumi K, Matsue Y, Nogi K, Sunayama T, Dotare T, Maeda D, Kagiyama N, Kasai T, Kitai T, Oishi S, Akiyama E, Suzuki S, Yamamoto M, Kida K, Okumura T, Nogi M, Ishihara S, Ueda T, Kawakami R, Siato Y, Minamino T. Usefulness of Incorporating Hypochloremia into the Get With The Guidelines–Heart Failure Risk Model in Patients with Acute Heart Failure. Am J Cardiol. 2022; 162:122-128
    144 Saito T, Yamaguchi T, Kuroda S, Kitai T, Yonetsu T, Kohsaka S, Torii S, Node K, Matsumoto S, Matsue Y, Kodama T. Impact of Body Mass Index on the Ou tcome of Japanese Patients with cardiovascular diseases and/or risk factors hospitalized with COVID-19 Infection. J Cardiol. 2022; 79:476-481.
    145 Maeda D, Matsue Y, Kagiyama N, Jujo K, Saito K, Kamiya K, Saito H, Ogasahara Y, Maekawa E, Konishi M, Kitai T, Iwata K, Wada H, Hiki M, Dotare T, Sunayama T, Kasai T, Nagamatsu H, Ozawa T, Izawa K, Yamamoto S, Aizawa N, Wakaume K, Oka K, Momomura SI, Minamino T. Sex differences in the prevalence and prognostic impact of physical frailty and sarcopenia among older patients with heart failure. Nutr Metab Cardiovasc Dis. 2022; 32:365-372
    146 Yamashita M, Kamiya K, Hamazaki N, Nozaki K, Saito H, Saito K, Ogasahara Y, Maekawa E, Konishi M, Kitai T, Iwata K, Jujo K, Wada H, Kasai T, Nagamatsu H, Ozawa T, Izawa K, Yamaoto S, Aizawa N, Wakaume K, Oka K, Momomura SI, Kagiyama N, Matsue Y. Work status before admission relates to prognosis in older patients with heart failure partly through social frailty. J Cardiol. 2022; 79:439-445.
    147 Ishiwata S, Kasai T, Sato A, Suda S, Matsumoto H, Shitara J, Yatsu S, Murata A, Shimizu M, Kato T, Hiki M, Matsue Y, Naito R, Daida H, Minamino T. Prognostic effect of sleep-disordered breathing on hospitalized patients following acute heart failure. Clin Res Cardiol. 2022; 111:663-672
    148 Sunayama T, Yatsu S, Matsue Y, Dotare T, Maeda D, Ishiwata S, Nakamura Y, Suda S, Kato T, Hiki M, Kasai T, Minamino T. Urinary liver-type fatty acid-binding protein as a prognostic marker in patients with acute heart failure. ESC Heart Fail. 2022;9:442-449.
    149 Emmans JE, ter Maaten JM, Matsue Y, Figarska SM, Sama IE, Cotter G, Cleland JGF, Davison BA, Felker GM, Givertz MM, Greenberg B, Pang PS, Severin T, Gimpelewicz C, Metra M, Voors AA, Teerlink JR. Worsening renal function in acute heart failure in the context of diuretic response. Eur J Heart Fail. 2022;24:365–374
    150 Sano T, Matsumoto S, Kuroda S, Kitai T, Yonetsu T, Kohsaka S, Torii S, Node K, Matsue Y. New-Onset Atrial Fibrillation in Patients with COVID-19 and Cardiovascular Disease: Insights from the CLAVIS-COVID registry. Circ J. 2022; 86:1237-1244
    151 Giang NM, Nguyen HH, Maeda D, Matsue Y. Tolvaptan add-on therapy to overcome loop Diuretic Resistance in Acute Heart Failure with renal dysfunction (DR-AHF): Design and Rationale. Front Cardiovasc Med. 2022;8:783181.
    152 Sunayama T, Matsue Y, Dotare T, Maeda D, Iso T, Morisawa T, Saitoh M, Yokoyama M, Jujo K, Takahashi T, Minamino T. Miltidomain frailty as a therapertic target in elderly patients with heart failure. Int Heart J. 2022;63:1-7
    153 Masumoto A, Kitai T, Matsumoto S, Kuroda S, Kohsaka S, Tachikawa R, Seo R, Doi A, Tomii K, Yonetsu T, Torii S, Komuro I, Hirata K, Node K, Matsue Y, Furukawa Y. Impact of serum lactate dehydrogenase on the short-term prognosis of COVID-19 with pre-existing cardiovascular diseases. J Cardiol. 2022;79:501-508
    154 Yoshioka K, Maeda D, Okumura T, Kida K, Oishi S, Akiyama E, Suzuki S, Yamamoto M, Mizukami A, Kuroda S, Kagiyama N, Yamaguchi T, Sasano T, Matsumura A, Kitai T, Matsue Y. Clinical implication of initial intravenous diuretic dose for acute decompensated heart failure. Sci Rep. 2022;12:2127
    155 Tanaka S, Kamiya K, Matsue Y, Yonezawa R, Saito H, Hamazaki N, Matsuzawa R, Nozaki K, Yamashita M, Wakaume K, Endo Y, Maekawa E, Yamaoka-Tojo M, Shiono T, Inomata T, Masuda T, Ako J. Effects of electrical muscle stimulation on physical function in frail older patients with acute heart failure: a randomized controlled trial. Eur J Prev Cardiol. 2022;in-press
    156 Maeda D, Matsue Y, Minamino T. Is combination therapy the key for treatment of heart failure with mid-range and preserved ejection fraction? Circ J. 2022; 86:1559-1561.
    157 Saito H, Matsue Y, Maeda D, Kamiya K, Kagiyama N, Endo Y, Yoshioka K, Mizukami A, Minamino T. Arm lean mass by dual-energy X-ray absorptiometry to predict mortality in older patients with heart failure. Arch Gerontol Geriatr. 2022; 101:104689
    158 Tanaka S, Kamiya K, Matsue Y, Yonezawa R, Saito H, Hamazaki N, Matsuzawa R, Nozaki K, Yamashita M, Wakaume K, Endo Y, Maekawa E, Yamaoka-Tojo M, Shiono T, Inomata T, Ako J. Efficacy and Safety of Acute Phase Intensive Electrical Muscle Stimulation in Frail Older Patients with Acute Heart Failure: Results from the ACTIVE-EMS Trial. J Cardiovasc Dev Dis. 2022; 9:99
    159 Nabeta T, Kitai T, Naruse Y, Taniguchi T, Yoshioka K, Tanaka H, Okumura T, Sato S, Baba Y, Kida K, Tamaki Y, Matsumoto S, Matsue Y. Risk stratification of patients with cardiac sarcoidosis: the ILLUMINATE-CS registry. Eur Heart J. 2022; 43:3450-3459
    160 Dotare T, Maeda D, Matsue Y, Minamino T. Effectiveness of methotrexate as a second-line treatment for cardiac sarcoidosis assessed. Eue Heart J Case Rep. 2022; 6:ytac226
    161 Saito H, Matsue Y, Maeda D, Kasai T, Kagiyama N, Endo Y, Zoda M, Mizukami A, Yoshioka K, Hashimoto T, Ishikawa K, Minamino T. Prognostic values of muscle mass assessed by dual-energy X-ray absorptiometry and bioelectrical impedance analysis in older patients with heart failure. Geriatr Gerontol Int. 2022; 22:610-615
    162 Sugimoto T, Mizuno A, Yoneoka D, Matsumoto S, Matsumoto C, Matsue Y, Ishida M, Nakai M, Iwanaga Y, Miyamoto Y, Node K. Hospitalizations for cardiovascular diseases during the early stage of the COVID-19 pandemic in Japan. Circ Rep. 2022; 4:353-362
    163 Kitai T, Nabeta T, Naruse Y, Taniguchi T, Miyakoshi C, Kurashima S, Miyoshi Y, Tanaka H, Okumura T, Baba Y, Furukawa Y, Matsue Y, Izumi C. Comparison between biopsy-proven versus clinically-diagnosed cardiac sarcoidosis. Heart. 2022; 108:1887-1894
    164 Shibahashi E, Jujo K, Kuroda S, Matsumoto S, Sano T, Kitai T, Yonetsu T, Kohsaka S, Torii S, Yamaguchi T, Kishi T, Komuro I, Hirata K, Node K, Matsue Y. Assessment of Thromboembolism Risk in COVID-19 Patients with Cardiovascular Disease Risk Factors: Analysis from the Japanese Nationwide registry. Thromb Res. 2022; 216:90-96
    165 Higaki A, Okayama H, Homma Y, Sano T, Kitai T, Yonetsu T, Torii S, Kohsaka S, Kuroda S, Node K, Matsue Y, Matsumoto S. Predictive Value of Neutrophil-to-lymphocyte Ratio for the Fatality of COVID-19 Patients Complicated with Cardiovascular Diseases and/or Risk Factors. Sci Rep. 2022; 12:13606.
    166 Iso T, Matsue Y, Mizukami A, Tokano T, Isoda K, Suwa S, Miyauchi K, Yanagisawa N, Okumura Y, Minamino T. Daprodustat for anaemia in patients with heart failure and chronic kidney disease: a randomised controlled study. ESC Heart Fail. 2022; 9:4291-4297.
    167 Abe T, Jujo K, Saito K, Ogasahara Y, Saito K, Saito H, Iwata K, Konishi M, Kitai T, Kasai T, Wada H, Momomura SI, Kagiyama N, Kamiya K, Yamashita M, Hamazaki N, Nozaki K, Maekawa E, Ako J, Matsue Y. The interaction between physical frailty and prognostic impact of heart failure medication in elderly patients. ESC Heart Fail. 2022;in-press
    168 Kaneko T, Kagiyama N, Nakamura Y, Dotare T, Sunayama T, Ishiwata S, Maeda D, Iso T, Kato T, Suda S, Hiki M, Matsue Y, Kasai T, Minamino T. External validation of the ACUTE HF score for risk stratification in acute heart failure. Int J Cardiol. 2022; 370:396-401
    169 Miyakuni S, Maeda D, Matsue Y, Yoshioka K, Dotare T, Sunayama T, Nabeta T, Naruse Y, Kitai T, Taniguchi T, Tanaka H, Okumura T, Baba Y, Matsumura A, Minamino T. The prognostic value of B-type natriuretic peptide in patients with cardiac sarcoidosis without heart failure: insights from ILLUMINATE-CS. J Am Heart Assoc. 2022; 11:e025803.
    170 Horiuchi Y, Matsue Y, Nogi K, Onitsuka K, Okumura T, Hoshino M, Shibata T, Daisuke N, Yoshida K, Sato S, Damman K, Voors AA, Kitai. Early treatment with a sodium-glocose co-transporter 2 inhibitor in high-risk patients with acute heart failure: rationale for and design of the EMPA-AHF trial. Am Heart J. 2022; S0002-8703 00325-8.
    171 Ishii K, Matsue Y, Miyauchi K, Miyazaki S, Hayashi H, Nishizaki Y, Nojiri S, Saito Y, Nagashima K, Okumura Y, Daida H, Minamino T. Predicting New-onset Heart Failure Hospitalization of Patients with Atrial Fibrillation: Development and External Validations of a Risk Score. Eur Heart J Qual Care Clin Outcomes. 2022; qcac085
    172 Kobayashi M, Ferreira JP, Matsue Y, Chikamori T, Ito S, Asakura M, Yamashina A, Kitakaze M. Effect of eplerenone on clinical stability of Japanese patients with acute heart failure. Int J Cardiol. 2022; S0167-5273 01938-6.
    173 Kurashima S, Kitai T, Matsue Y, Nogi K, Kagiyama N, Oishi S, Akiyama E, Suzuki S, Yamamoto M, Kida K, Okumura T, Nogi M, Ishihara S, Ueda T, Kawakami R, Furukawa Y, Saito Y, Izumi C. Trajectory of Serum Chloride Levels During Decongestive Therapy in Acute Heart Failure. Int J Cardiol. 2022; S0167-5273 01933-7
    174 Matsumoto S, Noda S, Torii S, Ikari Y, Kuroda S, Kitai T, Yonetsu T, Kohsaka S, Node K, Ikeda T, Matsue Y. Sex Differences in Clinical Outcomes Among Patients With COVID-19 and Cardiovascular Disease – Insights From the CLAVIS-COVID Registry. Circ Rep. 2022; 4:315-321
    175 Naito R, Kasai T. Obstructive coronary artery disease, a common and curable but critical comorbidity in acute decompensated heart failure. Eur J Heart Fail. 2022; 24: 2150-2151
    176 Murase K, Minami T, Hamada S, Gozal D, Takahashi N, Nakatsuka Y, Takeyama H, Tanizawa K, Endo D, Akahoshi T, Moritsuchi Y, Tsuda T, Toyama Y, Ohi M, Tomita Y, Narui K, Matsuyama N, Ohdaira T, Kasai T, Tsuboi T, Gon Y, Yamashiro Y, Ando S, Yoshimine H, Takata Y, Yoshihisa A, Tatsumi K, Momomura SI, Kuroda T, Morita S, Nakayama T, Hirai T, Chin K. Multimodal Telemonitoring for Weight Reduction in Patients With Sleep Apnea: A Randomized Controlled Trial. Chest. 2022; 162: 1373-1383
    177 Inoshita A, Matsumoto F, Ohba S, Sata N, Matsuoka R, Suzuki Y, Ito S, Koiwai H, Shiroshita N, Kasai T, Ikeda K. Severe obstructive sleep apnea after concurrent chemoradiotherapy for laryngeal and hypopharyngeal cancer. Auris Nasus Larynx. 2022; 49: 1078-1082
    178 Akashiba T, Inoue Y, Uchimura N, Ohi M, Kasai T, Kawana F, Sakurai S, Takegami M, Tachikawa R, Tanigawa T, Chiba S, Chin K, Tsuiki S, Tonogi M, Nakamura H, Nakayama T, Narui K, Yagi T, Yamauchi M, Yamashiro Y, Yoshida M, Oga T, Tomita Y, Hamada S, Murase K, Mori H, Wada H, Uchiyama M, Ogawa H, Sato K, Nakata S, Mishima K, Momomura SI. Sleep Apnea Syndrome (SAS) Clinical Practice Guidelines 2020. Respir Investig. 2022; 60: 3-32
    179 Naito R, Kasai T. Bereavement of a child as a risk of heart failure. Eur J Heart Fail. 2022; 24: 190-191.
    180 Tan JWC, Leow LC, Wong S, Khoo SM, Kasai T, Kojodjojo P, Sy DQ, Lee CP, Chirakalwasan N, Li HY, Koh N, Tan A, Ong TH, Aung AT, Toh ST, Lee CH. Asian Pacific Society of Cardiology Consensus Statements on the Diagnosis and Management of Obstructive Sleep Apnoea in Patients with Cardiovascular Disease. Eur Cardiol. 2022; 17:e16.
    181 Inoshita A, Sata N, Ohba S, Suzuki Y, Ito S, Shiroshita N, Kawana F, Kasai T, Higo R, Ikeda K, Matsumoto F. Impact of radiotherapy for head and neck cancer on obstructive sleep apnea: a prospective study., Ann Palliat Med., 2022; 11: 2631-2640.
    182 Tomita Y, Kimura Y, Kasagi S, Kasai T. Sleep Apnea and Abnormal Respiratory Patterns with Deep Sedation during Radiofrequency Catheter Ablation in Patients with Atrial Fibrillation. Rev Cardiovasc Med. 2022; 23: 121.
    183 Naito R, Kasai T, Narui K, Momomura SI. Association between Frequency of Central Respiratory Events and Clinical Outcomes in Heart Failure Patients with Sleep Apnea. J Clin Med. 2022; 11: 2403.
    184 Kawasaki Y, Kasai T, Sakurama Y, Sekiguchi A, Kitamura E, Midorikawa I, Shiroshita N, Kawana F, Ogasawara E, Kitade M, Koikawa N, Matsuda T. Evaluation of Sleep Parameters and Sleep Staging (Slow Wave Sleep) in Athletes by Fitbit Alta HR, a Consumer Sleep Tracking Device. Nat Sci Sleep. 2022; 14: 819-827.
    185 Hoshide S, Yoshihisa A, Tsuchida F, Mizuno H, Teragawa H, Kasai T, Koito H, Ando SI, Watanabe Y, Takeishi Y, Kario K. Pulse transit time-estimated blood pressure: a comparison of beat-to-beat and intermittent measurement. Hypertens Res. 2022; 45: 1001-1007.
    186 Dotare T, Ishiwata S, Matsue Y, Nakamura Y, Sunayama T, Maeda D, Yatsu S, Suda S, Kato T, Hiki M, Kasai T, Minamino T. Prevalence and Prognostic Relevance of Isolated Tubular Dysfunction in Patients With Acute Heart Failure. Circ J. 2022; 86: 709-714
    187 Saka K, Konishi M, Kagiyama N, Kamiya K, Saito H, Saito K, Ogasahara Y, Maekawa E, Misumi T, Kitai T, Iwata K, Jujo K, Wada H, Kasai T, Nagamatsu H, Ozawa T, Izawa K, Yamamoto S, Aizawa N, Makino A, Oka K, Kimura K, Tamura K, Momomura SI, Matsue Y. Impact of physical performance on exercise capacity in older patients with heart failure with reduced and preserved ejection fraction. Exp Gerontol. 2021; 156: 111626.
    188 Naito R, Daida H, Masuda D, Harada-Shiba M, Arai H, Bujo H, Ishibashi S, Koga N, Oikawa S, Yamashita S; FAME Study Group. Relation of Serum Lipoprotein(a) Levels to Lipoprotein and Apolipoprotein Profiles and Atherosclerotic Diseases in Japanese Patients with Heterozygous Familial Hypercholesterolemia: Familial Hypercholesterolemia Expert Forum (FAME) Study. J Atheroscler Thromb. 2022 Aug 1;29(8):1188-1200.
    189 Naito R, Miyauchi K, Yasuda S, Kaikita K, Akao M, Ako J, Matoba T, Nakamura M, Hagiwara N, Kimura K, Hirayama A, Matsui K, Ogawa H; AFIRE Investigators. Rivaroxaban Monotherapy vs Combination Therapy With Antiplatelets on Total Thrombotic and Bleeding Events in Atrial Fibrillation With Stable Coronary Artery Disease: A Post Hoc Secondary Analysis of the AFIRE Trial. JAMA Cardiol. 2022 Aug 1;7(8):787-794.
    190 Furuuchi R, Shimizu I, Yoshida Y, Katsuumi G, Suda M, Kubota Y, Walsh K, Minamino T. Endothelial SIRT-1 has critical role for the maintenance of capillarization in brown adipose tissue. iScience. 2022 Nov18, 25, 105424.
    191 Yoshida Y, Shimizu I, Shimada A, Nakahara K, Yanagisawa S, Kubo M, Fukuda S, Ishii C, Yamamoto H, Ishikawa T, Kano K, Aoki J, Hayashi Y, Ikegami R, Katsuumi G, Suda M, Ozaki K, Kashimura T, Izumi D, Yoshida Y, Okuda S, Ohta S, Okamoto S, Minokoshi Y, Oda K, Sasaoka T, Abe M, Sakimura K, Kubota Y, Yoshimura N, Kajimura S, Zuriaga M, Walsh K, Soga T and Minamino T. Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism. Sci Rep. 2022 Sep 1;12(1):14883.
    192 Suda M, Shimizu I, Katsuumi G, Yoshida Y, Matsumoto N, Yoshida Y, Katayama A, Wada J, Seki M, Suzuki Y, Okuda S, Ozaki K, Matsui M, Minamino T. Glycoprotein nonmetastatic melanoma protein B regulates lysosomal integrity and lifespan of senescent cells. Sci Rep. 2022, April 20, 6522
    193 Yoshida Y, Shimizu I, Minamino T. Capillaries as a therapeutic target for heart failure. J Atheroscler Thromb. 1;29(7):971-988. April1, 2022
    194 Yoshida Y, Shimizu I, Yung Ting Hsiao, Hayashi Y, Suda M, Katsuumi G, Ikegami R, Nakao M, Sakai R, Seki M, Suzuki Y, Okuda S, Soga T, Minamino T. Differing impact of phosphoglycerate mutase 1-deficiency on brown and white adipose tissue. iScience. 2022 Apr 18;25(5):104268
    195  Park N, Marquez J, Pham T, Ko TH, Youm JB, Kim M, Choi SH, Moon J, Flores J, Ko K, Rhee BD, Shimizu I, Minamino T, Ha JD, Hwang JY, Yang SJ, Park CS, Kim HK and Han J. Cereblon contributes to cardiac dysfunction by degrading Cav1.2α. European Heart Journal. 2022, May21;43(20):1973-1989
    196 Hsiao Y T, Shimizu I, Yoshida Y, Minamino T. Role of circulating molecules in age-related cardiovascular and metabolic disorders. Inflammation and regeneration. 42(1):2, Jan1, 2022.
    197 Takada S, Maekawa S, Furihata T, Kakutani N, Setoyama D, Ueda K, Nambu H, Hagiwara H, Handa H, Fumoto Y, Hata S, Masunaga T, Fukushima A, Yokota T, Kang D, Kinugawa S and Sabe H. Succinyl-CoA-based energy metabolism dysfunction in chronic heart failure. Proc Natl Acad Sci U S A. 2022;119:e2203628119
    198 Perea-Gil I, Seeger T, Bruyneel AAN, Termglinchan V, Monte E, Lim EW, Vadgama N, Furihata T, Gavidia AA, Arthur Ataam J, Bharucha N, Martinez-Amador N, Ameen M, Nair P, Serrano R, Kaur B, Feyen DAM, Diecke S, Snyder MP, Metallo CM, Mercola M and Karakikes I. Serine biosynthesis as a novel therapeutic target for dilated cardiomyopathy. European heart journal. 2022;43:3477-3489
    199 Nakajima S, Kawano H, Yamashiro K, Tanaka R, Kameda T, Kurita N, Hira K, Miyamoto N, Ueno Y, Watanabe M, Hirano T, Fujimoto S, Urabe T, Hattori N. Post-Treatment Plasma D-Dimer Levels Are Associated With Short-Term Outcomes in Patients With Cancer-Associated Stroke. Front Neurol. 2022 Apr 4;13:868137. doi: 10.3389/fneur.2022.868137.
    200 Noda S, Sato S, Fukuda T, Ueno S, Tada N, Hattori N. Impaired mitochondrial accumulation and Lewy pathology in neuron-specific FBXO7-deficient mice. Mol Brain. 2022 Jun 14;15(1):54. doi: 10.1186/s13041-022-00936-5.
    201 Nishioka K, Imai Y, Yoshino H, Li Y, Funayama M, Hattori N. Clinical Manifestations and Molecular Backgrounds of Parkinson’s Disease Regarding Genes Identified From Familial and Population Studies. Front Neurol. 2022 Jun 2;13:764917. doi: 10.3389/fneur.2022.764917.
    202 Ishikawa KI, Ishiguro M, Li Y, Nishioka K, Hattori N, Akamatsu W. Generation of three hiPSC clones from a Parkinson’s disease patient with a heterozygous variant of VPS35 p.D620N. Stem Cell Res. 2022 Apr;60:102739. doi:10.1016/j.scr.2022.102739.
    203 Yoshino H, Li Y, Nishioka K, Daida K, Hayashida A, Ishiguro Y, Yamada D, Izawa N, Nishi K, Nishikawa N, Oyama G, Hatano T, Nakamura S, Yoritaka A, Motoi Y, Funayama M, Hattori N; investigators of Japan Parkinson disease genetic study. Genotype-phenotype correlation of Parkinson’s disease with PRKN variants. Neurobiol Aging. 2022 Jun;114:117-128. doi:10.1016/j.neurobiolaging.2021.12.014.
    204 Daida K, Nishioka Y, Li Y, Yoshino H, Funayama M, Hattori N, Nishioka K. A complex form of hereditary spastic paraplegia harboring a novel variant, p.W1515*, in the SPG11 gene. eNeurologicalSci. 2022 Jan 3;26:100391. doi:10.1016/j.ensci.2021.100391.
    205 Hoshino Y, Noto D, Sano S, Tomizawa Y, Yokoyama K, Hattori N, Miyake S. Dysregulated B cell differentiation towards antibody-secreting cells in neuromyelitis optica spectrum disorder. J Neuroinflammation. 2022 Jan 6;19(1):6. doi: 10.1186/s12974-021-02375-w.
    206 Riku Y, Iwasaki Y, Ishigaki S, Akagi A, Hasegawa M, Nishioka K, Li Y, Riku M, Ikeuchi T, Fujioka Y, Miyahara H, Sone J, Hattori N, Yoshida M, Katsuno M, Sobue G. Motor neuron TDP-43 proteinopathy in progressive supranuclear palsy and corticobasal degeneration. Brain. 2022 Aug 27;145(8):2769-2784. doi:10.1093/brain/awac091.
    207 Tezuka T, Taniguchi D, Sano M, Shimada T, Oji Y, Tsunemi T, Ikeda A, Li Y, Yoshino H, Ogata J, Shiba-Fukushima K, Funayama M, Nishioka K, Imai Y, Hattori N. Pathophysiological evaluation of the LRRK2 G2385R risk variant for Parkinson’s disease. NPJ Parkinsons Dis. 2022 Aug 5;8(1):97.
    208 Cossu D, Ruberto S, Yokoyama K, Hattori N, Sechi LA. Efficacy of BCG vaccine in animal models of neurological disorders. Vaccine. 2022 Jan 24;40(3):432-436. doi: 10.1016/j.vaccine.2021.12.005.
    209 Daida K, Shimonaka S, Shiba-Fukushima K, Ogata J, Yoshino H, Okuzumi A, Hatano T, Motoi Y, Hirunagi T, Katsuno M, Shindou H, Funayama M, Nishioka K, Hattori N, Imai Y. α-Synuclein V15A Variant in Familial Parkinson’s Disease Exhibits a Weaker Lipid-Binding Property. Mov Disord. 2022 Oct;37(10):2075-2085. doi: 10.1002/mds.29162.
    210 Ikeda A, Imai Y, Hattori N. Neurodegeneration-associated mitochondrial proteins, CHCHD2 and CHCHD10-what distinguishes the two? Front Cell Dev Biol. 2022 Sep 9;10:996061.
    211 Sasazawa Y, Souma S, Furuya N, Miura Y, Kazuno S, Kakuta S, Suzuki A, Hashimoto R, Hirawake-Mogi H, Date Y, Imoto M, Ueno T, Kataura T, Korolchuk VI, Tsunemi T, Hattori N, Saiki S. Oxidative stress-induced phosphorylation of JIP4 regulates lysosomal positioning in coordination with TRPML1 and ALG2. EMBO J. 2022 Nov 17;41(22):e111476. doi:10.15252/embj.2022111476.
    212 Inoshita T, Liu JY, Taniguchi D, Ishii R, Shiba-Fukushima K, Hattori N, Imai Y. Parkinson disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila. iScience. 2022 Nov 2;25(12):105476. doi:10.1016/j.isci.2022.105476.
    213 Cossu D, Yokoyama K, Sato S, Noda S, Sakanishi T, Sechi LA, Hattori N. Age related immune modulation of experimental autoimmune encephalomyelitis in PINK1 knockout mice. Front Immunol. 2022 Nov 17;13:1036680. doi:10.3389/fimmu.2022.1036680.
    214 Noda S, Sato S, Fukuda T, Ueno S, Tada N, Hattori N. Impaired mitochondrial accumulation and Lewy pathology in neuron-specific FBXO7-deficient mice. Mol Brain. 2022 Jun 14;15(1):54. doi: 10.1186/s13041-022-00936-5.
    215 Riku Y, Iwasaki Y, Ishigaki S, Akagi A, Hasegawa M, Nishioka K, Li Y, Riku M, Ikeuchi T, Fujioka Y, Miyahara H, Sone J, Hattori N, Yoshida M, Katsuno M, Sobue G. Motor neuron TDP-43 proteinopathy in progressive supranuclear palsy and corticobasal degeneration. Brain. 2022 Aug 27;145(8):2769-2784. doi:10.1093/brain/awac091.
    216 Sakurai A, Tsunemi T, Ishiguro Y, Okuzumi A, Hatano T, Hattori N. Comorbid alpha synucleinopathies in idiopathic normal pressure hydrocephalus. J Neurol. 2022 Apr;269(4):2022-2029. doi: 10.1007/s00415-021-10778-1.
    217 Sakurai A, Tsunemi T, Shimada T, Kawamura K, Nakajima M, Miyajima M, Hattori N. Effect of comorbid Parkinson’s disease and Parkinson’s disease dementia on the course of idiopathic normal pressure hydrocephalus. J Neurosurg. 2022 Mar 11:1-8. doi: 10.3171/2022.1.JNS212282.
    218 Hira K, Ueno Y, Miyamoto N, Nakajima S, Kijima C, Hattori N. Association of blood eicosapentaenoic acid levels with intracerebral hemorrhage during the COVID-19 pandemic: preliminary experience from a single-center in Japan. BMC Neurol. 2022 Apr 5;22(1):128. doi: 10.1186/s12883-022-02657-7.
    219 Hira K, Ueno Y, Watanabe M, Shimura H, Kurita N, Miyamoto N, Haginiwa H, Yamashiro K, Hattori N, Urabe T. Impact of D-dimer for pathologic differentiation on transesophageal echocardiography in embolic stroke of undetermined source: a single-center experience. BMC Neurol. 2022 Sep 8;22(1):338. doi: 10.1186/s12883-022-02867-z.
    220 Nakajima S, Kawano H, Yamashiro K, Tanaka R, Kameda T, Kurita N, Hira K, Miyamoto N, Ueno Y, Watanabe M, Hirano T, Fujimoto S, Urabe T, Hattori N. Post-Treatment Plasma D-Dimer Levels Are Associated With Short-Term Outcomes in Patients With Cancer-Associated Stroke. Front Neurol. 2022 Apr 4;13:868137. doi:10.3389/fneur.2022.868137.
    221 Kanazawa K, Miyamoto N, Hira K, Kijima C, Ueno Y, Hattori N. Baseline platelet count may predict short-term functional outcome of cerebral infarction. BMC Neurol. 2022 Aug 25;22(1):314. doi: 10.1186/s12883-022-02845-5.
    222 Kataura T, Sedlackova L, Otten EG, Kumari R, Shapira D, Scialo F, Stefanatos R, Ishikawa KI, Kelly G, Seranova E, Sun C, Maetzel D, Kenneth N, Trushin S, Zhang T, Trushina E, Bascom CC, Tasseff R, Isfort RJ, Oblong JE, Miwa S, Lazarou M, Jaenisch R, Imoto M, Saiki S, Papamichos-Chronakis M, Manjithaya R, Maddocks ODK, Sanz A, Sarkar S, Korolchuk VI. Autophagy promotes cell survival by maintaining NAD levels. Dev Cell. 2022 Nov 21;57(22):2584-2598.e11.
    223 Yusuke Tsuji, Aurelien Kerever, Toshiki Furukawa, Koji Kamagata, Yuya Saito, Shigeki Aoki, Junichi Hata, Hideyuki Okano, Kenta Kobayashi, Takuya Okada, Ken Miya, Kazuko Keino-Masu, Masayuki Masu, Eri Arikawa-Hirasawa Diffusion magnetic resonance tractography-based evaluation of commissural fiber abnormalities in a heparan sulfate endosulfatase-deficient mouse brain. Magnetic resonance imaging 88 123-1312022
    224 Eri Arikawa-Hirasawa Impact of the Heparan Sulfate Proteoglycan Perlecan on Human Disease and Health. American journal of physiology. Cell physiology 2022
    225 Satoshi Nakada, Yuri Yamashita, Seiya Akiba, Takeru Shima, Eri Arikawa-Hirasawa Myocyte Culture with Decellularized Skeletal Muscle Sheet with Observable Interaction with the Extracellular Matrix Bioengineering 9(7) 309-309 2022
    226 Nozomi Hayashiji, Genri Kawahara, Xing Xu, Tomohiko Fukuda, Aurelien Kerever, Jianguo Gu, Yukiko K. Hayashi, Eri Arikawa-Hirasawa α-1,6-Fucosyltransferase Is Essential for Myogenesis in Zebrafish Cells 12(1) 144-144 2022
    227 Noda S, Sato S, Fukuda T, Ueno S, Tada N, Hattori N. Impaired mitochondrial accumulation and Lewy pathology in neuron-specific FBXO7-deficient mice. Mol Brain. 2022;15:54.
    228 Cossu D, Yokoyama K, Sato S, Noda S, Sakanishi T, Sechi LA, Hattori N. Age related immune modulation of experimental autoimmuneencephalomyelitis in PINK1 knockout mice. Front Immunol. 2022;13:1036680.
    229 Akiko Suzuki; Chihiro Iwaya; Kenichi Ogata; Hiroki Yoshioka; Junbo Shim; Isei Tanida; Masaaki Komatsu; Norihiro Tada; Junichi Iwata. Impaired GATE16-mediated exocytosis in exocrine tissues causes Sjögren’s syndrome. Cellular and Molecular Life Sciences. 2022, 79(6):307. doi: 10.1007/s00018-022-04334-x.
    230  Hanbing Xu, Madoka Nakajima, Ikuko Ogino, Kaito Kawamura, Chihiro Akiba, Chihiro Kamohara, Koichiro Sakamoto, Kostadin Karagiozov, Eri Nakamura, Norihiro Tada, Hajime Arai, Akihide Kondo, Masakazu Miyajima. Ptpn20 deletion in H-Tx rats facilitates cotransporter-mediated water transport in the choroid plexus: evidence of genetic risk for hydrocephalus in an experimental study. Fluids and Barriers of the CNS, 2022, 19(1): 39. doi: 10.1186/s12987-022-00341-z.
    231 Fujiwara N, Miyahara K, Nakazawa-Tanaka N, Oishi Y, Akazawa C, Tada N, Yamakata A. Differentiation of enteric neural crest cells transplanted from SOX10-Venus mouse embryonic stem cells into the gut of the endothelin receptor B null mouse model. Pediatric Surgery International. 2022, 39(1):18. doi: 10.1007/s00383-022-05318-5.
    232 Natsume S, Baba H, Maeshima H, Saida T, Yoshinari N, Shimizu K, SuzukiT.Clinical course and serum amyloid β levels in elderly patients with major depressive disorder.J Affect Disord.2022 Oct 15;315:156-161.
    233 Atake K, Hori H, Kageyama Y, Koshikawa Y, Igata R, Tominaga H, Katsuki A, Bando H, Sakai S, Nishida K, Takekita Y, Kato T, Kinoshita T, KatoM. Pre-treatment plasma cytokine levels as potential predictors of short-term remission of depression. World J Biol Psychiatry. 2022 Dec;23(10):785-793.
    234 Obata Y, Kubota-Sakashita M, Kasahara T, Mizuno M, Nemoto T, Kato T.Phenethylamine is a substrate of monoamine oxidase B in the paraventricular thalamic nucleus.Sci Rep.2022 Jan 7;12(1):17
    235 Sugawara H, Bundo M, Kasahara T, Nakachi Y, Ueda J, Kubota-Sakashita M, Iwamoto K, Kato T.Cell-type-specific DNA methylation analysis of the frontal cortices of mutant Polg1 transgenic mice with neuronal accumulation of deleted mitochondrial DNA. Mol Brain . 2022 Jan 6;15(1):9
    番号 全著者名,論文名,掲載誌名, 掲載年;巻(号):ページ番号
    1 Shigeki Yamada, Masatsune Ishikawa, Madoka Nakajima and Kazuhiko Nozaki.Ventriculoperitoneal shunt surgery and postoperative shunt valve pressure adjustment.Front Neurol, 2022; 12:798488. doi: 10.3389/fneur.2021.798488
    2 Sakamoto K, Horikoshi K, Kawamura K, Iimura Y, Kondo A Surgical Site Infections in Hydrocephalus Surgery and Pediatric Neurosurgery, 2022, 50(5):1035-104
    3 K Tsuboshima, M Kurihara, K Seyama. Current opinion and comparison of surgical procedures for the treatment of primary spontaneous pneumothorax. Expert Rev Respir Med., 2022;16:161-171.
    4 Maeda D, Dotare T, Matsue Y, Teramoto K, Sunayama T, Tromp J, Minamino T. Blood pressure in heart failure management and prevention. Hypertens Res. 2022;in-press.
    5 Nishioka K, Imai Y, Yoshino H, Li Y, Funayama M, Hattori N. Clinical Manifestations and Molecular Backgrounds of Parkinson’s Disease Regarding Genes Identified From Familial and Population Studies. Front Neurol. 2022 Jun 2;13:764917.
    6 Baba H, Kito S, Nukariya K, Takeshima M, Fujise N, Iga J, Oshibuchi H,Kawano M, Kimura M, Mizukami K, Mimura M; Committee for Treatment Guidelines of Mood Disorders, Japanese Society of Mood Disorders.Guidelines for diagnosis and treatment of depression in older adults:A report from the Japanese Society of mood disorders.Psychiatry Clin Neurosci . 2022 Jun;76(6):222-234.
    番号 全著者名,書籍名,出版社名, 出版年, ページ番号等
    1 Sasazawa Y, Hattori N, Saiki S:  Development of autophagy enhancers for Parkinson’s disease. Autophagy Dysfunction in Alzheimer’s Disease and Dementia, Editors: Tadanori Hamano & Tatsuro Mutoh, Academic Press Book-Elsevier,2022 UK, 305-320, total pages are 356,  2022, • No. of pages: 356 • Language: English • Copyright: © Academic Press 2022 • Published: August 20, 2022 • Imprint: Academic Press • Paperback ISBN: 9780323899062  • eBook ISBN: 9780323899147
    番号 全著者名,論文名,掲載誌名, 掲載年;巻(号):ページ番号
    1 Kazuki Nomura, Hiroharu Suzuki, Yasushi Iimura, Takumi Mitsuhashi, Samantha Tamrakar, Tetsuya Ueda, Kazuaki Nishioka, Keiko Fusegi, Mari Tada, Madoka Nakajima, Akiyoshi Kakita, Hidenori Sugano.Epilepsy surgery without lipoma removal for temporal lobe epilepsy associated with lipoma in the Sylvian fissure.Acta Neurochir. 165(1):265-269, 2022
    2 Madoka Nakajima.Surgical Techniques for Young Neurosurgeons: LP-Shunt.Hydrocephalus Society Global Webinar Series Series on iNPH Part 9: Treatment, , 09. Apr. 2022
    3 Madoka Nakajima.Idiopathic Normal Pressure Hydrocephalus.the Joint Annual Meeting ISMRM-ESMRMB and the ISMRT 31st Annual Meeting in London, England, UK, 11. May. 2022
    4 Koichi Oshio, Masao Yui, Seiko Shimizu, Shinya Yamada, Madoka Nakajima, Chihiro Akiba, Hideki Bandai, Masakazu Miyajima.Observing Clearance Pathway in Alzheimer Patients Using T2 Component Analysis.the Joint Annual Meeting ISMRM-ESMRMB and the ISMRT 31st Annual Meeting in London, England, UK, 07-12. May. 2022
    5 Kosuke Fukumori, Noboru Yoshida, Hidenori Sugano, Madoka Nakajima, Toshihisa Tanaka.Epileptic Spike Detection by Recurrent Neural Networks with Self-Attention Mechanism.ICASSP 2022, Singapore,22, May 2022
    6 Madoka Nakajima.LP-shunt.the Pre-meeting educational seminar, Hydrocephalus2022. Gothenburg, Sweden, 9. Sep. 2022
    7 Madoka Nakajima.Surgical technical perspectives. How to pay for necessary development? .Hydrocephalus2022. Gothenburg, Sweden, 11. Sep. 2022
    8 Chihiro Kamohara, Madoka Nakajima, Masakazu Miyajima Kaito Kawamura, Chihiro Akiba, Koichiro Sakamoto, Hanbing Xu, Ikuko Ogino, Kostadin Karagiozov Akihide Kondo.The distribution of dopamine transporter accumulation in the striatum reflects cognitive function and gait ability of patients with iNPH.Hydrocephalus2022. Gothenburg, Sweden, 12. Sep. 2022
    9 Hanbing Xu, Masakazu Miyajima, Madoka Nakajima, Ikuko Ogino, Kaito Kawamura, Chihiro Akiba, Chihiro Kamohara, Koichiro Sakamoto, Kostadin Karagiozov, Eri Nakamura, Nobuhiro Tada,Hajime Arai and Akihide Kondo,Ptpn20 deletion in H-Tx rats enhances phosphorylation of the NKCC1 cotransporter in the choroid plexus.Hydrocephalus2022. Gothenburg, Sweden, 10. Sep. 2022
    10 Kaito Kawamura, Madoka Nakajima, Masakazu Miyajima, Chihiro Akiba, Koichiro Sakamoto, Chihiro Kamohara, Hanbing Xu, Ikuko Ogino, Shinya Yamada, Kostadin Karagiozov, Akihide Kondo.TIME-DEPENDENT BIOMARKER LEVEL CHANGE ALONG WITH PROGRESSION OF CSF STAGNATION IN IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS.Hydrocephalus2022. Gothenburg, Sweden, 12. Sep. 2022
    11 Y Sekimoto, Y Suzuki, K Kanamori, I Kobayashi, H Ienaga, K Takahashi. A case of negative-pressure pulmonary oedema after first-time electroconvulsive therapy. Respirol Case Rep., 2022; 10(6): e0956.
    12 I Sumiyoshi, SI Iwakami, M Hara, H Matsuda, K Takahashi. Solitary brain tuberculoma without active pulmonary lesions in an elderly patient: A case report. Geriatr Gerontol Int., 2022; 22(6): 490-491.
    13 S Okamoto, I Kobayashi, H Moriyama, M Tanimura, K Kadoya, H Ienaga, T Kikuchi, K Takahashi. Silicosis-related pleural effusion diagnosed using elemental analysis of the pleural fluid cell block: A case report. Respire Med Case Rep., 2022; 37: 101665.
    14 Y Tanabe, T Shukuya, Y Nagata, T Watanabe, K Seto, R Takahashi, K Masuda, K Miura, Tajima K, Hiki M, Hayashi T, Suzuki K, Takahashi K. Successful restart of chemotherapy in a patient with primary mediastinal nonseminomatous germ cell tumor after COVID-19 infection. Thorac Cancer., 2022; 13(18): 2654-2658.
    15 Nishino K, Akimoto T, Mitsuoka H, Terajima Y, Arai Y, Masui Y, Mimori T, Koike K, Takahashi K, Sekiya M. A Case of Tuberculosis-related Cerebral Venous Sinus Thrombosis and Pulmonary Thromboembolism Successfully Treated with Edoxaban. Respir Med Case Rep., 2022; 139: 101736.
    16 S Kataoka, K Matsuno, K Sugano, K Takahashi. Thyroid storm induced by combined nivolumab and ipilimumab immunotherapy in advanced non-small cell lung cancer. BMJ Case Rep., 2022; 15(10): e250696.
    17 S Okamoto, K Koike, M Sekiya, K Nishino, T Mimori, K Takahashi. Late relapse of ulcerative colitis presenting as tracheobronchitis: a case report. J Med Case Rep., 2022; 16(1): 414.
    18 Hasui H, Iseki T, Ueno Y, Kamiyama D, Miyamoto N, Kijima C, Hira K, Komatsu N, Hattori N. Recurrent and Multiple Intracerebral Hemorrhages in Polycythemia Vera Secondary to Myelofibrosis: A Case Report and Literature Review. Case Rep Neurol. 2022 Jun 7;14(2):274-280. doi: 10.1159/000525171.
    19 Kamo H, Oyama G, Nishioka K, Funayama M, Hattori N. Deep Brain Stimulation for a Patient with Familial Parkinson’s Disease Harboring CHCHD2 p.T61I. Mov Disord Clin Pract. 2022 Mar 4;9(3):407-409. doi: 10.1002/mdc3.13428.
    番号 発表者名,発表タイトル(題目・演題・課題等),学会名,場所,発表年月日等
    1 Asano S., Ogawa A., Tochigi R., Tanaka M., Osada T., Kamagata K., Aoki S., Konishi S. Neural correlates for other’s equity concern modulating response to distribution in ultimatum game. OHBM 2022, Glasgow, UK, June 7, 2022
    2 Nakajima K., Osada T., Ogawa A., Tanaka M., Oka S., Kamagata K., Aoki S., Oshima Y., Tanaka S., Konishi S. Sustained suppression of brain activity induced by transcranial ultrasound stimulation in humans. SfN 2022, San Diego, USA, November 14, 2022
    3 Ogawa A., Osada T., Tanaka M., Suda A., Nakajima K., Oka S., Kamagata K., Aoki S., Oshima Y., Tanaka S., Hattori N., Konishi S. Subjective food evaluation recruits hypothalamic interactions with reward-related regions. SfN 2022, San Diego, USA, November 14, 2022
    4 Madoka Nakajima.Lumboperitoneal Shunt for idiopathic Normal Pressure Hydrocephalus.Hydrocephalus Society Global Webinar Series Series on iNPH Part 3: Treatment, 29.Jan. 2022
    5 M Kato, S Soma, Y Arai, S Nakazawa, H Motomura, Y Ochi, I Sumiyoshi, J Watanabe, H Ihara, K Kadoya, S Togo, S Sasaki, K Takahashi. The Differences in Efficacy and Tolerability of Nintedanib Based on the Severity of Idiopathic Pulmonary Fibrosis. ATS 2022 International Conference, San Francisco, CA, USA, May 13-18, 2022(Online)
    6 H Sasano, N Harada, Y Sandhu, Y Tanabe, S Harada, T Watanabe, Y Sato, T Nishimaki, S Abe, S Ueda, A Goto, T Takeshige, K Matsuno, J Ito, T Nagaoka, R Atsuta, A Chiba, H Akiba, S Miyake, K Takahashi. Mucosal Associated Invariant T Cells May Have Any Protective Role against Type 2 Airway Inflammation in OVA-Induced Murine Asthma Model. ATS 2022 International Conference, San Francisco, CA, USA, May 13-18, 2022(Online)
    7 Y Sandhu, N Harada, S Harada, H Sasano, S Abe, S Ueda, T Nishimaki, Y Sato, T Watanabe, T Takeshige, K Matsuno, J Ito , H Akiba, K Takahashi. Role of MAP3K19 in allergic airway inflammation of asthma. ATS 2022 International Conference, San Francisco, CA, USA, May 13-18, 2022(Online)
    8 S Nakazawa, M Kato, S Soma, H Namba, Y Arai, H Motomura, Y Ochi, K Kurokawa, I Sumiyoshi, J Watanabe, H Ihara, T Asao, S Shimada, S Togo, S Sasaki, K Takahashi. Safety of Immune Checkpoint Inhibitors in Advanced Non-Small Cell Lung Cancer Patients with Interstitial Lung Abnormalities or Disease. ATS 2022 International Conference, San Francisco, CA, USA, May 13-18, 2022(Online)
    9 H Motomura, M Kato, T Oni, Y Ochi, E Hayakawa, S Soma, T Akimoto, Y Arai, I Sumiyoshi, J Watanabe, H Ihara, K Kadoya, S Togo, S Sasaki, K Takahashi. Difference in Clinical Features and Prognosis of Patients Diagnosed with Idiopathic Pleuroparenchymal Fibroelastosis by Subtype Using New Japanese Clinical Diagnostic Criteria. ATS 2022 International Conference, San Francisco, CA, USA, May 13-18, 2022(Online)
    10 M Kato, S Sasaki, E Hayakawa, S Soma, Y Arai, S Nakazawa, H Motomura, I Sumiyoshi, J Watanabe, Y Ochi, H Ihara, K Kadoya, S Togo, K Takahashi. Early administration of nintedanib after the onset acute exacerbation in patients with interstitial lung disease. ERS International Congress 2022, BARCELONA, Spain, Sep 4-6, 2022
    11 Y Suzuki, T Nagaoka, Y Nagata, T Yoshida, T Tsutsumi, S Kuriyama, Y Tabe, K Takahashi. Exploratory study of predictive factors of disease progression in the early stage of COVID-19 (Oral). The 26th Congress of the Asian Pacific Society of Respirology(APSR), Seoul, Korea, 17-20 Nov, 2022
    12 Y Nagata, T Nagaoka, Y Kuroda, S Hotta, T Okuma, K Masuda, N Sakamoto, T Nishimaki, K Kurokawa, T Miyawaki, T Asao , R Kanemaru, T Mimori, S Kuriyama, Y Mitsuishi, M Ichikawa, N Shimada, T Hayashi, K Takahashi. Efficacy and safety of the transbronchial lung cryobiopsy: a single-center retrospective study in Japan.  The 26th Congress of the Asian Pacific Society of Respirology(APSR), Seoul, Korea, 17-20 Nov, 2022
    13 T Nishimaki, K Kurokawa, T Miyawaki, T Asao, R Kanemaru, T Mimori, S Kuriyama, Y Mitsuishi, M Ichikawa, N Shimada, T Hayashi, K Takahashi. Efficacy and safety of the transbronchial lung cryobiopsy: a single-center retrospective study in Japan. The 26th Congress of the Asian Pacific Society of Respirology(APSR), Seoul, Korea, 17-20 Nov, 2022
    14 S Abe, N Harada, Y Sandhu, H Sasano, Y Tanabe, S Harada, A Goto, T Watanabe, Y Sato, T Nishimaki, Y Kato, S Ueda, T Takeshige, J Ito, R Atsuta, K Takahashi. The impact of one-year treatment with dupilumab in patients with severe asthma. The 26th Congress of the Asian Pacific Society of Respirology(APSR), Seoul, Korea, 17-20 Nov, 2022
    15 Tajima M, Togo S, Ko R, Koinuma Y, Sumiyoshi I, Torasawa M, Kikuchi N, Shiraishi A, Sasaki S, Kyogoku S, Kuwatsuru R, Takahashi K. The recommended image features of peripheral lung parenchymal targets for diagnosis by CT-guided needle biopsy. The 26th Congress of the Asian Pacific Society of Respirology(APSR), Seoul, Korea, 17-20 Nov, 2022
    16 笹野仁史,原田紀宏,原田園子,竹重智仁,三道ユウキ,田辺悠記,石森絢子,松野圭,長岡鉄太郎,伊藤潤,熱田了,出原賢治,高橋和久.Circulating CD69-positive MAIT cells, neutrophils, and serum periostin as a novel predictive biomarker for mepolizumab therapy (メポリズマブ治療有効例を予測する新規バイオマーカーとしての末梢血中CD69陽性MAIT細胞、好中球、血清ペリオスチン値の可能性). 第31回国際喘息学会日本・北アジア部会,東京,2022年11月25-26日
    17 三道ユウキ,原田紀宏,笹野仁史,田辺悠記,原田園子,佐藤良彦,西牧孝泰,安部寿美子,上田翔子,竹重智仁,長岡鉄太郎,伊藤潤,熱田了,高橋和久.Novel biomarkers of clinical remission with anti-IL-5 receptor antibody therapy in patients with severe asthma.(重症気管支喘息における抗IL-5受容体抗体治療による臨床的寛解に関する新規バイオマーカー).第31回国際喘息学会日本・北アジア部会,東京,2022年11月25-26日
    18 安部寿美子,原田紀宏,三道ユウキ,笹野仁史,田辺悠記,原田園子,佐藤良彦,西牧孝泰,加藤由香,上田翔子,竹重智仁,伊藤潤,熱田了,高橋和久.Effectiveness of dupilumab treatment in patients with severe asthma. (重症気管支喘息患者に対するデュピルマブの効果の検討).第31回国際喘息学会日本・北アジア部会,東京,2022年11月25-26日
    19 上田翔子,原田紀宏,原田園子,後藤愛,笹野仁史,三道ユウキ,田辺悠記,安部寿美子,竹重智仁,松野圭,長岡鉄太郎,伊藤潤,熱田了,高橋和久.Longterm clinical effectiveness for more than three years of omalizumab therapy in patients with severe asthma(3年以上オマリズマブを使用した重症気管支喘息症例の検討).第31回国際喘息学会日本・北アジア部会,東京,2022年11月25-26日
    20 N Harada. 教育講演3: 移行期医療という内科医へのバトン(The baton called transitional medicine from pediatrician to internal medicine doctors). 第31回国際喘息学会日本・北アジア部会,東京,2022年11月25-26日
    21 N Harada. スポンサードシンポジウム1: 2型炎症を標的とした生物学的製剤治療による臨床的寛解の可能性
    (The possibility for clinical remission with biologic therapy targeting type 2 inflammation)第31回国際喘息学会日本・北アジア部会,東京,2022年11月25-26日
    22 宮﨑彩記子 Incremental prognostic value of left atrial strain in predicting cardiotoxicity after chemotherapy: sub-analysis from the SUCCOR study. American College of Cardiology 71th annual meeting, poster presentation  Washington, DC 2022/4/2-4
    23 鍵山暢之 Identification of valvular heart disease from body surface electrocardiogram: a prospective multicenter study.  American College of Cardiology 71th annual meeting Washington, DC 2022/4/2-4
    24 Yui O.Nozaki, Shinichiro Fujimoto, Chihiro Aoshima, Yuki Kamo, Yuko O.Kawaguchi, Kazuhisa Takamura, Ayako Kudo, Daigo Takahashi, Makoto Hiki, Tomotaka Dohi, Nobuo Tomizawa, Tohru Minamino. Additional Prognostic value of plaque analysis for on-site CT-derived FFR in coronary CT angiography on nidterm prognosis. The American College of Cardiology 71nd Annual Scientific Session, Washington DC, USA 2022.4
    25 Daigo Takahashi , Shinichiro Fujimoto , Yui O.Nozaki , Ayako Kudo , Chihiro Aoshima , Yuki Kamo , Yuko O.Kawaguchi , Kazuhisa Takamura , Makoto Hiki , Hideyuki Sato , Nobuo Tomizawa , Tohru Minamino. Usefulness of new method to quantify pericoronary adipose tissue on ECG-gated non-contrast chest CT scan. The American College of Cardiology 71nd Annual Scientific Session, Washington DC, USA 2022.4
    26 Abulimiti A, Naito R, Kasai T, Prognostic Value of Cheyne-Stokes Respiration and Nutritional Status in Acute Heart Failure Patients (Poster)., European Society of Cardiology Heart Failure 2022, 2022.5
    27 Yatsu S, Kasai T, Matsumoto H, Impact of sleep disordered breathing on overnight changes of atrial stiffness in patients with heart failure (Poster)., American College of Cardiology 2022: 71st Annual Scientific Session & Expo, 2022.4
    28 Daigo Takahashi, Shinichiro Fujimoto, Yui O.Nozaki, Ayako Kudo, Yuko O.Kawaguchi, Kazuhisa Takamura, Makoto Hiki, Hideyuki Sato, Nobuo Tomizawa, Tohru Minamino. Clinical Impact of Novel Pericoronary Adipose Tissue Measurement on ECG-gated Non-contrast Chest CT Scan. ESC Congress, Barcelona, 2022.8
    29 Yui O. Nozaki, Shinichiro Fujimoto, Daigo Takahashi, Yuko O. Kawaguchi, Ayako Kudo, Chihiro Aoshima, Yuki Kamo, Kazuhisa Takamura, Makoto Hiki, Tomotaka Dohi, Nobuo Tomizawa, Tohru Minamino. Additional Clinical Impact of Plaque Analysis for On-site CT-derived FFR in coronary CT angiography on Midterm Prognosis. ESC Congress, Barcelona, 2022.8
    30 M Ito, D Maeda, Y Matsue, Y Shiraishi, T Dotare, T Sunayama, K Nogi, S Kohsaka, T Yoshikawa, Y Saito, T Minamino. Increasing the class of foundational medication for heart failure is associated with improved prognosis in hospitalized patients with heart failure with reduced or mildly reduced ejection fraction. European Society of Cardiology(ESC) Congress, 2022/8/26-29,Barcelona,Spain.
    31 宮﨑彩記子  Baseline left atrial reservoir strain provides independent and incremental prognostic value in predicting chemotherapy related cardiotoxicity European Society of Cardiology congress 2022 BARCELONA 2022/8/27
    32 葛西隆敏、Diagnosis, treatment and clinical imlications of sleep apnea in patients with hypertension、第29回国際高血圧学会、京都、2022/10/13
    33 Yohko Yoshida, Ippei Shimizu, Tohru Minamino. Brown adipose tissue dysfunction promotes metabolic disorder in a failing heart. The 29th Scientific Meeting of International Society of Hypertension, Poster session, 13-16 Oct., 2022, Kyoto/WEBハイブリッド開催.
    34 Funamizu Takehiro, IwataHiroshi, Moriya Soshi, Koike Takuma, Yasuda Hidetoshi, Chikata Yuichi, Doi Shinichiro, Okazaki Shinya, Daida Hiroyuki, Minamino Tohru  The association between impairment of HDL cholesterol efflux capacity and the degree of aortic valvular calcification in patients with severe aortic stenosis  22ND INTERNATIONAL VASCULAR BIOLOGY MEETING  California, USA  2022/10/14
    35 Hiroyuki Omori, Hitoshi Matsuo, James Earls, Yoshihiro Sobue, Shinichiro Fujimoto, Yui Nozaki, Gaku Nakazawa, Kuniaki Takahashi, Kazuhiro Osawa, Ryo Okubo, Umihiko Kaneko, Hideyuki Sato, Takashi Kajiya, Toru Miyoshi, Keishi Ichikawa, Mitsunori Abe, Toshiro Kitagawa, Hiroki Ikenaga, Mike Saji, Nobuo Iguchi, Takeshi Ijichi, Hiroshi Mikamo, Akira Kurata, Masao Moroi, raisuke iijima, Tami Crabtree, James K Min, Rine Nakanishi. Optimal Hounsfield Threshold for Lipid-Rich Plaque by Artificial Intelligence-Enabled Quantitative CT Using Near-Infrared Spectroscopy. American Heart Association, 95th Scientific Session, Chicago, USA 2022.11
    36 Ryota Nishio, Dohi Tomotaka, Tatsuya Fukase, Mitsuhiro Takeuchi, Norihito Takahashi, Endo Hirohisa, Shinichiro Doi, Iwao Okai, Hiroshi Iwata, Shinya Okazaki, Katsumi Miyauchi,  Hiroyuki Daida, Tohru Minamino The Estimated Appendicular Skeletal Muscle Mass Predicts Adverse Outcomes in Patients Under 65 Years With Coronary Artery Disease  American Heart Association Scientific Session 2022 Chicago, 2022/11/5
    37 Tatsuya Fukase, Dohi Tomotaka, Shinichiro Fujimoto, Yui Nozaki, ryota nishio, Ayako Kudo, Mitsuhiro Takeuchi, Norihito Takahashi, Yuichi Chikata, Endo Hirohisa, Yuko Kawaguchi, Shinichiro Doi, Hiroki Nishiyama, Makoto Hiki, Iwao Okai, Hiroshi Iwata, Takayuki Yokoyama, Shinya Okazaki, Katsumi Miyauchi, Hiroyuki Daida, Tohru Minamino Relationship Between Coronary HIPs on Non-Contrast T1-WI by CMR and Vulnerable Plaque Features by NIRS-IVUS American Heart Association Scientific Session 2022  Chicago, 2022/11/5
    38 Tatsuya Fukase, Shinichiro Doi, Dohi Tomotaka, ryota nishio, Norihito Takahashi, Yuichi Chikata, Endo Hirohisa, Hiroki Nishiyama, Iwao Okai, Hiroshi Iwata, Shinya Okazaki, Hiroyuki Daida, Tohru Minamino, Katsumi Miyauchi Therapeutic Window of Low-Dose Prasugrel for Platelet Reactivity in the Chronic Phase of Post-Percutaneous Coronary Intervention: The Chaperon Study American Heart Association Scientific Session 2022  Chicago, 2022/11/5
    39 T.Dotare, T.Iso, T.Kato, S.Suda, M.Hiki, T.Kasai, T.Minamino, D.Maeda, Y.Matsue, Y.Nakamura, Y.Akama, Y.Tsujimura, T.Sunayama, S.Ishiwata, S.Yatsu.  Low Estimated Protein Intake Is Associated With Poor Prognosis In Patients With Acute Heart Failure. American Heart Association Scientific Session 2022(AHA2022)2022/11/5-7,Chicago,USA
    40 Hsiao YT, Shimizu I, Yoshida Y, Katsuumi G, Minamino T. Circulating Obesity Associated Pro-fibrotic Protein as a Brown Adipokine Promotes Liver and Heart Fibrosis in Obese NASH Mice. American Heart Association (AHA)-2022 Scientific Section. November 6-8th, 2022. Chicago IL, USA. (poster presentation)
    41 Chieh-Lun Hsiao、口述発表、Glycoprotein Nonmetastatic Melanoma Protein B Regulates Lysosomal Integrity and Lifespan of Senescent Cells. AHA Congress, Scientific Session, Chicago. 2022/11/5
    42 Sasazawa Y., Souma S., Miura Y., Suzuki A., Kakuta S., Hashimoto R., Imoto M., Ueno T., Hattori N., Saiki S. JIP4 phosphorylation regulates lysosomal positioning in coordination with TRPML1 and ALG2. The 10th international symposium on Autophagy. Sapporo, Japan. Oct. 2022
    43 Saiki S, Sasazawa Y. Polyamine metabolic changes and autophagy in Parkinson’s disease. The 10th international symposium on Autophagy. Sapporo, Japan. Oct. 2022
    44 Date Y., Sasazawa Y., Imoto M., Saya H., Itakura E., Saiki S., Hattori N.Chemical Screening based on the lysosomal positioning against Parkinson’s disease. The 10th international symposium on Autophagy. Sapporo, Japan. Oct. 2022
    45 Kato T. Neurobiology of bipolar disorder: Toward the understanding of action mechanisms of anti-bipolar drugs. 5th Japan-UK Neuroscience Symposium. Karuizawa, September 21/2022
    番号 全著者名,論文名,掲載誌名, 掲載年;巻(号):ページ番号
    1 谷田以誠, 山口隼司, 角田宗一郎, 内山安男、エポン樹脂包埋試料中の蛍光タンパク質を観察する ~In-resin CLEMへのアプローチ、解剖学雑誌 2022, 97:13-16.
    2 内山安男、リソソームカテプシン 分布と役割、生体の科学 2022, 73:191-195.
    3 秋山理.頭部打撲に対する治打撲一方の治療効果.漢方と最新治療 第31巻第4号(通巻123号)P235-240
    4 高橋 哲也, 森沢 知之, 齊藤 正和, 澤 龍一, 谷口 香, 北原 エリ子, 西崎 祐史, 野尻 宗子, 森澤 文登, 南野 徹, 藤原 俊之, 代田 浩之 レッドゾーンで新型コロナウイルス感染症患者に対応する理学療法士の心理的ストレスについて 理学療法学 2022; 48: 620-627.
    5 須田 将吉, 南野 徹 老化細胞除去治療の発展と抗老化ワクチン 循環器内科 2022; 92: 568-575.
    6 須田 将吉, 南野 徹【アンチエイジング科学と未来医療】老化細胞除去治療 Precision Medicine 2022; 5: 1178-1182.
    7 須田 将吉, 南野 徹 老化細胞除去ワクチンの開発 臨床免疫・アレルギー科 2022; 78: 199-205.
    8 須田 将吉, 南野 徹【加齢と上手に付き合うために(2)-来るべき加齢現象に備える-】老化細胞の除去とその可能性 保健の科学 2022; 64: 606-611
    9 須田 将吉, 南野 徹 老化細胞除去ワクチンの開発 Anti-Aging Business 2022; 5: 22-25.
    10 須田 将吉, 南野 徹 老化細胞除去ワクチン 老年科. 2022; 5(5): 297-302.
    11 須田 将吉, 南野 徹 【老化細胞を標的としたSenolyticsへの挑戦 加齢性疾患を引き起こすメカニズムの理解と治療への展開】循環器疾患と細胞老化 実験医学. 2022; 40(3): 384-389.
    12 磯部 光章, 南野 徹, 前嶋 康浩, 横山 広行 心不全の新しい治療薬によるこれからの診療 社会的に重要な課題は高齢心不全の増加と患者のケアにある Vita. 2022; 39(1): 1-14.
    13 林 英守、鈴木まどか  「ICD/CRT治療 腕の見せどころ」 治す13.ICD/CRT治療における遠隔モニタリングの重要性  Heart View』2022年11月号
    14 葛西隆敏., 不眠症-研究・診療の最新知識 不眠関連疾患 16. 高血圧と不眠., 医学のあゆみ., 2022, 281:1015-1019
    15 葛西隆敏., VIII. COPD病態 up-to-date 9. 心不全の心拍管理 日本臨床80/増刊6 COPDと気管支喘息、その周辺疾患 -病態・診断・治療の最新動向-., 2022, 80/増刊6:526-532
    16 葛西隆敏., Medical Science Review 各論1:循環器疾患と睡眠呼吸障害. 特集「睡眠時無呼吸症候群と含む睡眠呼吸障害-最新の動向」, Vita., 2022, 39 (160):32-39
    17 葛西隆敏., <各論>2.在宅睡眠循環器検査のウェアラブルシステムと将来像<循環器領域> 特集テーマ:ウェアラブル診断システムとしての簡易睡眠検査を再考する., 睡眠医療., 2022, 16:21-27
    18 葛西隆敏., 解説 テーマ:1. 心不全と低酸素ストレス:睡眠時無呼吸症候群管理の重要性. 特集/右心不全の話題., 循環器内科., 2022, 91:236-242
    19 葛西隆敏., 8. 心房細動・心不全患者への包括的なSAS治療. 特集/睡眠時無呼吸症候群(SAS)の診療ガイドライン2020と診療の現状., 呼吸器内科., 2022, 41:357-361
    20 佐藤彰洋, 内藤亮, 葛西隆敏., 心不全患者の睡眠呼吸障害., 麻酔., 2022, 71:252-263
    番号 全著者名,論文名,掲載誌名, 掲載年;巻(号):ページ番号
    1 野崎 侑衣、藤本進一郎:虚血性心疾患の早期診断を目指した冠動脈CT. Medical Practice. 2022; 39巻2号219-223
    2 野崎侑衣、鍵山暢之:たこつぼ症候群をマルチモダリティ画像診断で診断する. Heart View, 2022; 5月号, 558-563
    3 野崎 侑衣、藤本進一郎:OMTの効果と、見える化. CATHLAB JIN. 2022; 5巻2号66-69,
    4 藤本進一郎:慢性冠動脈疾患における冠動脈CT・FFRCTの現状と課題. 臨床核医学. 2022; 55巻5号 69-72.
    5 野崎 侑衣、藤本進一郎:FFRCTの現状と課題. 冠疾患誌. 2022; 4: 9-14
    6 加藤隆生,西崎祐二.「心停止後の生存者フォローアップ」, 日本の臨床サポート,エルゼア・ジャパン
    7 加藤隆生. 「心不全による浮腫の鑑別・評価・治療」,月刊薬事,株式会社じほう,2022年10月号(Vol.64 No.13)
    8 加藤隆生.「睡眠時無呼吸症候群と心障害」,「診断と治療」110巻12号(特集:日常診療で見る二次性心筋症・全身疾患関連の心障害),株式会社 診断と治療社
    9 原田紀宏.重症気管支喘息治療のアップデート 生物学的製剤 ベンラリズマブ, 呼吸器内科, 2022; 41(1): 26-31
    10 宮脇太一, 宿谷威仁.肺癌新時代における一般内科医の役割 実地医家が知っておくべき治療の実際 非小細胞肺癌の内科治療,  Medical Practice, 2022; 39(3): 413-420
    11 加藤元康, 山川英晃. CT検診で見つかるような軽微な間質性陰影(ILA)を見つけた場合の対処法は? HRCTにおいて分布と線維化の有無、進行の程度を定期的に確認する(Q&A), 日本医事新報, 2022; 5117: 54-55
    12 朝尾哲彦. Central Nervous System Tumor 脳腫瘍 転移性脳腫瘍Update 転移性脳腫瘍患者に対する薬物療法 肺がん転移性脳腫瘍に対する薬物療法,  癌と化学療法, 2022; 49(6): 648-653
    13 吉田隆司, 長岡鉄太郎, 鈴木宜史.【肺高血圧症の病態から治療戦略を考える】肺血管収縮と肺高血圧, 呼吸器内科, 2022; 41(6): 537-543
    14 原田紀宏, 伊藤潤. 【COPDと気管支喘息、その周辺疾患-病態・診断・治療の最新動向-】喘息 診断へのアプローチ One airway、one disease, 日本臨床, 2022; 80巻増刊: 298-303
    15 佐藤匡, 瀬山邦明. 【COPDと気管支喘息、その周辺疾患-病態・診断・治療の最新動向-】COPD病態up-to-date α1-アンチトリプシン欠乏症. 日本臨床, 2022; 80巻増刊: 481-486
    16 塩田智美. 【睡眠呼吸障害(SDB)と認知症】間欠的低酸素と認知症, 睡眠医療, 2022; 16(2): 139-143
    17 坂本奈穂, 宿谷威仁. 【肺癌の遺伝子診断の現状と展望】次世代シークエンサーを用いたパネル検査 オンコマインTarget TestマルチCDxシステム, 呼吸器内科, 2022; 42(1): 39-44
    18 三浦啓太. がん悪液質に対する最新薬物治療, 呼吸器内科, 2022; 42(1): 97-104
    19 光石陽一郎, 瀬山邦明. 【びまん性肺疾患-病態・臨床の最新知見-】診断と治療 病理が特徴的で稀なびまん性肺疾患 肺リンパ脈管筋腫症, 日本臨床, 2022; 80(9): 1485-1491
    20 加藤元康. 【呼吸器診断マスター-病歴,身体所見,画像所見でここを見る!】疾患別”臨床医の頭の中” 特発性間質性肺炎 上葉優位型肺線維症にfocusして, 呼吸器ジャーナル, 2022; 70(4): 498-503
    21 瀬山邦明.【呼吸器診断マスター-病歴,身体所見,画像所見でここを見る!】疾患別”臨床医の頭の中” 嚢胞性肺疾患, 呼吸器ジャーナル, 2022; 70(4): 528-535
    22 佐藤匡, 瀬山邦明.【呼吸器難病の課題と展望】α1-アンチトリプシン欠乏症, 呼吸器内科, 2022; 42(5): 517-521
    23 高橋和久, 阿部瞳, 舛井嘉大. 【最新臨床肺癌学-診断・治療の最新動向-】進化する肺癌臨床 肺癌遺伝子診断と保険診療,
    日本臨床, 2022; 80巻増刊: 116-123
    24 舛井嘉大, 宿谷威仁. 【最新臨床肺癌学-診断・治療の最新動向-】治療 薬物療法 ドライバー遺伝子変異/転座陰性, PD-L1 TPS50%未満,もしくは不明, 日本臨床, 2022; 80巻増刊: 534-539
    25 Shimada T, Tsunemi T, Iimura Y, Sugano H, Hattori N. [Reactivation of latent viruses in Neurology]. Rinsho Shinkeigaku. 2022 Sep 28;62(9):697-706. Japanese. doi: 10.5692/clinicalneurol.cn-001734.
    26 加藤忠史(2022) 気分障害の神経生物学 生体の科学 73: 468-469.
    27 加藤忠史(2022)  臨床につながる気分障害のモデルマウス : 双極性障害のモデルマウスを中心として 臨床精神医学 51: 1159-1164.
    番号 全著者名,書籍名,出版社名, 出版年, ページ番号等
    1 中島 円, 川村海渡.水頭症-脳脊髄液動態への理解と治療に迫る. iNPHの診断.医学書院. 2022, 脳神経外科50(2)298-308
    2 中島 円.Annual Review 神経,Ⅱ. 本年の動向. 11) iNPHの治療のオーバービュー:現状と課題.中外医学社, 2022, 132-140
    3 中島 円.脳神経外科学レビュー, 正常圧水頭症 診断と治療. 総合医学社, 2022, 270-278
    4 南野 徹 生物の寿命延長 老化・長寿命の基盤研究最前線 2022年9月18日初版 エヌ・ティー・エス ISBN: 978-4-86043-773-2
    5 横山美帆,本沢晶雄:おうちでできる若返りトレーニング 現代けんこう出版, 東京, 2022. 36頁
    6 横山美帆,本沢晶雄:スキマ時間でできる心も体も健康になれるカンタントレーニング現代けんこう出版, 東京, 2022. 4頁
    7 横山美帆,島田和典 包括的心臓リハビリテーション 後藤葉一, 南山堂, 東京, 2022
    8 宮﨑彩記子  【特集/循環器デジタルヘルス各論】『解説3.がん治療関連心機能障害評価におけるGlobal Longitudinal Strain測定』 「循環器内科」第91巻4号(2022年4月号)
    9 鍵山暢之  【特集/循環器デジタルヘルス各論】『心機能評価と機械学習』 「循環器内科」第91巻4号(2022年4月号)
    10 金子智洋、鍵山暢之【超音波検査・診断最前線-POCUSの最新動向を中心に-】『循環器領域におけるPOCUSの実際 -POCUSが変える循環器診療-』   「月刊インナービジョン」第37巻5号(2022年5月号)
    11 金子智洋、鍵山暢之  【特集 いま,これだけは押さえたい弁膜症診療】『僧帽弁閉鎖不全症と弁・弁輪のリモデリング』    「Heart View」第26巻4号(2022年3月号)
    12 齋藤洋、末永祐哉. Frailtyと心不全. 治療. 104 ;2022:171-174.
    13 末永祐哉. 日経ドラッグインフォメーション. 292 ;2022:025-036
    14 末永祐哉. 入門 ケースから学ぶ循環器集中治療ドリル. 日本集中医療学会
    15 砂山 勉、末永祐哉、堂垂大志.INTENSIVIST.14 ;2022:535-542
    16 砂山 勉、堂垂大志、末永祐哉.HEART nursing.35 ;2022:042-050
    17 堂垂大志、松本絋毅.月間薬事.64 ;2022:055-057
    18 砂山 勉、松本絋毅.月間薬事.64 ;2022:058-063-
    19 須田翔子,葛西隆敏:『7.心血管病と睡眠時無呼吸症候群』,循環器内科 第92巻6号,科学評論社,東京,2022
    20 清水逸平, 南野徹. 老化におけるRAA系の意義、CARDIAC PRACTICE(メディカルレビュー社)、Vol32, No2, 42-47, 2022.
    21 清水逸平, 南野徹. 論文図表を読む作法、寒冷刺激試験、2022年、p160-161(羊土社)(単行本)
    22 清水逸平, 南野徹. 脂肪細胞の老化と肥満、糖尿病、Geriatric Medicine(老年医学). 60(10):931-936, 2022
    23 清水逸平, 南野徹. 循環器疾患に対する選択的老化細胞除去による先制医療の可能性、循環器内科(科学評論社)、92(4):434-439、2022
    24 清水逸平, 南野徹. 心疾患と老化、Bio Clinica(北隆館)、Vol37 No14、33-37、Dec2022
    25 降旗高明,清水逸平, 南野徹.  心血管疾患と免疫 腎臓内科 科学評論社,16(4):467-476,2022