業績

  • 2010年

    ｜　Ａ．原著・症例報告

    Ａ．原著・症例報告

    • Shinohara M, Sato N, Kurinami H, Takeuchi D, Takeda S, Shimamura M, Yamashita T, Uchiyama Y, Rakugi H, Morishita R. Reduction of brain b-amyloid(Abeta) by fluvastatin, a hydroxymethylglutaryl- CoA reductase inhibitor, through increase in degradation of amyloid precursor protein C-terminal fragments (APP-CTFs) and Abeta clearance. J Biol Chem.2010 Jul 16;285(29):22091-102.
    • Terada K, Yamada J, Hayashi Y, Wu Z, Uchiyama Y, Peters C, Nakanishi H Involvement of cathepsin B in the processing and secretion of interleukin-1beta in chromogranin A stimulated microglial. Glia. 2010 Jan 1;58(1):114-24.
    • Sun L, Wu Z, Baba M, Peters C, Uchiyama Y, Nakanishi H. Cathepsin B-dependent motor neuron death after nerve injury in the adult mouse. Biochem Biophys Res Comm.2010 Aug 27;399(3):391-5.
    • Lee J-H, Yu WH, Kumar A, Lee S, Mohan PS, Peterhoff CM, Wolfe DM, Martinez-Vicente M, Massey AC, Sovak G, Uchiyama Y, Westaway D, Cuervo AM, Nixon RA. Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations. Cell.2010 Jun 25;141(7):1146-58.
    • Tizon B, Sahoo S, Yu H, Gauthier S, Kumar AR, Mohan P, Figliola M, Pawlik M, Grubb A, Uchiyama Y, Bandyopadhyay U, Cuervo AM, Nixon RA, Levy E. Induction of autophagy by cystatin C: a mechanism that protects murine primary cortical neurons and neuronal cell lines. PLoS One.2010 Mar 23;5(3):e9819.
    • Hadano S, Otomo A, Kunita R, Suzuki-Utsunomiya A, Akatsuka A, Koike M, Aoki M, Uchiyama Y, Itoyama Y, Ikeda JE. Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1H46R-expressing mouse ALS model by disturbing endolysosomal trafficking. PLoS One.2010 Mar 22;5(3):e9805.
    • Shimada N, Ohno-Matsui K, Iseki S, Koike M, Uchiyama Y, Wang J, Yoshida T, Sato T, Peters C, Mochizuki M, Morita I. Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization. Am J Pathol.2010 May;176(5):2571-80.
    • Shibata M, Yoshimura K, Tamura H, Ueno T, Nishimura T, Inoue T, Sasaki M, Koike M, Arai H, Kominami E, Uchiyama Y. LC3, a microtubule-associated protein1A/B light chain3, is involved in cytoplasmic lipid droplet formation. Biophys Biochem Res Commun.2010 Mar 5;393(2):274-9.
    • ☆Yagita Y, Horie K, Yamanaka I, Koinuma S, Shigeyoshi Y, Kawakami K, Takeda J, Uchiyama Y.Chondrogenesis during the ES cell differentiation in vitro. PNAS.2010 107:3846-3851
    • Tamura H, Shibata M, Koike M, Sasaki M, Uchiyama Y. Atg9A protein, an autophagy-related membrane protein, is localized in the neurons of mouse brains. J Histochem Cytochem.2010 May;58(5):443-53.
    • Hattori N. [Molecular genetics of familial Parkinson’s disease]. Rinsho Shinkeigaku. 2010 Nov;50(11):863. Japanese.
    • Ogaki K, Noda K, Fukae J, Furuya T, Hirayama T, Fujishima K, Hattori N, Okuma Y. [Cryptococcal meningitis successfully treated with liposomal amphotericin B and voriconazole in an elderly patient]. Brain Nerve. 2010 Dec;62(12):1337-40. Japanese.
    • Funayama M, Tomiyama H, Wu RM, Ogaki K, Yoshino H, Mizuno Y, Hattori N. Rapid screening of ATP13A2 variant with high-resolution melting analysis. Mov Disord. 2010 Oct 30;25(14):2434-7.
    • Yoshino H, Tomiyama H, Tachibana N, Ogaki K, Li Y, Funayama M, Hashimoto T, Takashima S, Hattori N. Phenotypic spectrum of patients with PLA2G6 mutation and PARK14-linked parkinsonism. Neurology. 2010 Oct 12;75(15):1356-61.
    • Tanaka Y, Tanaka R, Liu M, Hattori N, Urabe T. Cilostazol attenuates ischemic brain injury and enhances neurogenesis in the subventricular zone of adult mice after transient focal cerebral ischemia. Neuroscience. 2010 Dec 29;171(4):1367-76.
    • Sekine T, Kagaya H, Funayama M, Li Y, Yoshino H, Tomiyama H, Hattori N. Clinical course of the first Asian family with Parkinsonism related to SNCA triplication. Mov Disord. 2010 Dec 15;25(16):2871-5.
    • Fukae J, Tanaka S, Hattori N. Retroperitoneal fibrosis secondary to pergolide therapy. Intern Med. 2010;49(15):1687.
    • Noda K, Tani M, Fukae J, Fujishima K, Hattori N, Okuma Y. Isolated proximal leg paresis due to a small cortical infarction. Intern Med. 2010;49(15):1633-6.
    • Li L, Funayama M, Tomiyama H, Li Y, Yoshino H, Sasaki R, Kokubo Y, Kuzuhara S, Mizuno Y, Hattori N. No evidence for pathogenic role of GIGYF2 mutation in Parkinson disease in Japanese patients. Neurosci Lett. 2010 Aug 2;479(3):245-8.
    • Oyama G, Yoshimi K, Natori S, Chikaoka Y, Ren YR, Funayama M, Shimo Y, Takahashi R, Nakazato T, Kitazawa S, Hattori N. Impaired in vivo dopamine release in parkin knockout mice. Brain Res. 2010 Sep 17;1352:214-22.
    • Miyamoto N, Tanaka Y, Ueno Y, Tanaka R, Hattori N, Urabe T. Comparison of clinical backgrounds with anterior versus posterior circulation infarcts. J Stroke Cerebrovasc Dis. 2010 Sep-Oct;19(5):393-7.
    • Kawajiri S, Machida Y, Saiki S, Sato S, Hattori N. Zonisamide reduces cell death in SH-SY5Y cells via an anti-apoptotic effect and by upregulating MnSOD. Neurosci Lett. 2010 Sep 6;481(2):88-91.
    • Ueno Y, Shimada Y, Tanaka R, Miyamoto N, Tanaka Y, Hattori N, Urabe T. Patent foramen ovale with atrial septal aneurysm may contribute to white matter lesions in stroke patients. Cerebrovasc Dis. 2010;30(1):15-22.
    • Tani M, Hayakawa H, Yasuda T, Nihira T, Hattori N, Mizuno Y, Mochizuki H. Ectopic expression of α-synuclein affects the migration of neural stem cells in mouse subventricular zone. J Neurochem. 2010 Nov;115(4):854-63.
    • Shiotsuki H, Yoshimi K, Shimo Y, Funayama M, Takamatsu Y, Ikeda K, Takahashi R, Kitazawa S, Hattori N. A rotarod test for evaluation of motor skill learning. J Neurosci Methods. 2010 Jun 15;189(2):180-5.
    • Kawajiri S, Saiki S, Sato S, Sato F, Hatano T, Eguchi H, Hattori N. PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy. FEBS Lett. 2010 Mar 19;584(6):1073-9.
    • Fukae J, Noda K, Fujishima K, Takahashi T, Hattori N, Okuma Y. Subacute longitudinal myelitis associated with Behcet’s disease. Intern Med. 2010;49(4):343-7.
    • Kawanabe T, Yoritaka A, Shimura H, Oizumi H, Tanaka S, Hattori N. Successful treatment with Yokukansan for behavioral and psychological symptoms of Parkinsonian dementia. Prog Neuropsychopharmacol Biol Psychiatry. 2010 Mar 17;34(2):284-7.
    • Miyamoto N, Tanaka R, Shimura H, Watanabe T, Mori H, Onodera M, Mochizuki H, Hattori N, Urabe T. Phosphodiesterase III inhibition promotes differentiation and survival of oligodendrocyte progenitors and enhances regeneration of ischemic white matter lesions in the adult mammalian brain. J Cereb Blood Flow Metab. 2010 Feb;30(2):299-310.