業績

  • 2015年

    1. Ito Y, Kawano H, Kanai F, Nakamura E, Tada N, Takai S, Horie S, Arai H, Kobayashi T, Hino O. Establishment of Tsc2-deficient rat embryonic stem cells. Int J Oncol. 2015 May; 46(5): 1944-1952.

    2. Liu C, Kanamaru Y, Watanabe T, Tada N, Horikoshi S, Suzuki Y, Liu Z, Tomino Y. Targeted IgA Fc receptor I (FcαRI) therapy in the early intervention and treatment of pristane induced lupus nephritis in mice. Clin Exp Immunol. 2015 Sep; 181(3): 407-416.

    3. Yoshihara T, Shimada K, Fukao K, Sai E, Sato-Okabayashi Y, Matsumori R, Shiozawa T, Alshahi H, Miyazaki T, Tada N, Daida H. Omega 3 polyunsaturated fatty acids suppress the development of aortic aneurysms through the inhibition of macrophage-mediated inflammation. Circ J. 2015; 79(7): 1470-1478.

    4. Schultz M, Kimura T, Akiyama O, Shimoji K, Spors B, Miyajima M, Thomale UW: Endoscopic and microsurgical treatment of Sylvian fissure arachnoid cysts – clinical and radiological outcome. World Neurosurg. 2015 Mar 25

    5. Moriya M, Miyajima M, Nakajima M, Ogino I, Arai H: Impact of cerebrospinal fluid shunting for idiopathic normal pressure hydrocephalus on the amyloid cascade. PLoS One 2015 Mar 30

    6. Kazui H, Miyajima M, Mori E, Ishikawa M; SINPHONI-2 Investigators: Lumboperitoneal shunt surgery for idiopathic normal pressure hydrocephalus (SINPHONI-2): an open-label randomized trial. Lancet Neurol 14(6): 585-594, 2015

    7. Nakajima M, Miyajima M, Ogino I, Akiba C, Sugano H, Hara T, Fusegi K, Karagiozov K, Arai H: Cerebrospinal fluid biomarkers for prognosis of long-term cognitive treatment outcomes in patients with idiopathic normal pressure hydrocephalus. J Neurol Sci 2015 Jul 2

    8. Tsutsumi S, Ogino I, Miyajima M, Ito M, Arai H, Yasumoto Y: Cerebrospinal fluid drainage through the diploic and spinal epidural veins. J Anat 2015 June 3

    9. Kageyama H, Miyajima M, Ogino I, Nakajima M, Shimoji K, Fukai R, Miyake N, Nishiyama K, Mastumoto N, Arai H: Panventriculomegaly with a wide foramen of Magendi and a large cisterna magna. J Neurosurg (in press)

    10. Miyajima M, Arai H: Evaluation of the production and absorption of cerebrospinal fluid. Neurol Med Chir (Tokyo) 55(8): 647-656, 2015

    11. Komuro Y, Shimizu A, Shimoji K, Miyajima M, Arai H: Posterior cranial vault distraction osteogenesis with barrel stave osteotomy in the treatment of craniosynostosis. Neurol Med Chir (Tokyo) 55(8): 617-623, 2015

    12. Kawai E, Shibata N, Nagata T, Shinagawa S, Tagai K, Ohnuma T, Shimazaki H, Toda A, Kasanuki K, Takayama T, Suzuki A, Nakayama K, Yamada H, Arai H.Genetic Association Between KIBRA Polymorphism and Alzheimer’s Disease with in a JapanesePopulation.　Neuromolecular Med.2015:Jun;17(2):170-7.
    　
    13. Nagata T, Kobayashi N, Ishii J, Shinagawa S, Nakayama R, Shibata N, Kuerban B, Ohnuma T, Kondo K, Arai H, Yamada H, Nakayama K.　Association between DNA Methylation of the BDNF Promoter Region and Clinical Presentation in Alzheimer’s Disease. Dement Geriatr Cogn Dis Extra.2015:Mar 4;5(1):64-73.

    14. Ito Y, Kawano H, Kanai F, Nakamura E, Tada N, Takai S, Horie S, Arai H, Kobayashi T, Hino O. Establishment of Tsc2-deficient rat embryonic stem cells. Int J Oncol. 2015 May; 46(5): 1944-1952.

    15. Liu C, Kanamaru Y, Watanabe T, Tada N, Horikoshi S, Suzuki Y, Liu Z, Tomino Y. Targeted IgA Fc receptor I (FcαRI) therapy in the early intervention and treatment of pristane induced lupus nephritis in mice. Clin Exp Immunol. 2015 Sep; 181(3): 407-416.

    16. Yoshihara T, Shimada K, Fukao K, Sai E, Sato-Okabayashi Y, Matsumori R, Shiozawa T, Alshahi H, Miyazaki T, Tada N, Daida H. Omega 3 polyunsaturated fatty acids suppress the development of aortic aneurysms through the inhibition of macrophage-mediated inflammation. Circ J. 2015; 79(7): 1470-1478.

    17． Watanabe T, Hanajima R, Shirota Y, Tsutsumi R, Shimizu T, Hayashi T, Terao Y, Ugawa Y, Katsura M, Kunimatsu A, Ohtomo K, Hirose S, Miyashita Y, Konishi S. Effects of rTMS over presupplementary motor area on fronto-basal-ganglia network activity during stop-signal task. Journal of Neuroscience, 35, 4813-4823, 2015

    18． Ueno S, Miyamoto N, Shimura H, Ueno Y, Watanabe M, Hayashi A, Hattori N, Urabe T. Successful immune moderation treatment for progressive encephalomyelitis with rigidity and myoclonus. Intern Med. 2015;54(2):219-21.

    19． Matsuo H, Tomiyama H, Satake W, Chiba T, Onoue H, Kawamura Y, Nakayama A, Shimizu S, Sakiyama M, Funayama M, Nishioka K, Shimizu T, Kaida K, Kamakura K, Toda T, Hattori N, Shinomiya N. ABCG2 variant has opposing effects on onset ages of Parkinson’s disease and gout. Ann Clin Transl Neurol. 2015 Mar;2(3):302-6.

    20． Fusegi K, Yoritaka A, Hattori N, Mori H. Automatic behavior in Parkinson’s disease.
    Parkinsonism Relat Disord. 2015 Jan;21(1):84-5.

    21． Nishioka K, Oyama G, Yoshino H, Li Y, Matsushima T, Takeuchi C, Mochizuki Y, Mori-Yoshimura M, Murata M, Yamasita C, Nakamura N, Konishi Y, Ohi K, Ichikawa K, Terada T, Obi T, Funayama M, Saiki S, Hattori N. High frequency of beta-propeller protein-associated neurodegeneration (BPAN) among patients with intellectual disability and young-onset parkinsonism. Neurobiol Aging. 2015 May;36(5):2004.e9-2004.e15.

    22． Kino Y, Washizu C, Kurosawa M, Oma Y, Hattori N, Ishiura S, Nukina N. Nuclear localization of MBNL1: splicing-mediated autoregulation and repression of repeat-derived aberrant proteins. Hum Mol Genet. 2015 Feb 1;24(3):740-56.

    23． Kurosawa M, Matsumoto G, Kino Y, Okuno M, Kurosawa-Yamada M, Washizu C, Taniguchi H, Nakaso K, Yanagawa T, Warabi E, Shimogori T, Sakurai T, Hattori N, Nukina N. Depletion of p62 reduces nuclear inclusions and paradoxically ameliorates disease phenotypes in Huntington’s model mice. Hum Mol Genet. 2015 Feb 15;24(4):1092-105.

    24． Yamashiro K, Funabe S, Tanaka R, Fukumura Y, Takanashi M, Yao T, Hattori N. Primary aortic sarcoma: a rare but critical cause of stroke. Neurology. 2015 Feb 17;84(7):755-6.

    25． Asano T, Koike M, Sakata S, Takeda Y, Nakagawa T, Hatano T, Ohashi S, Funayama M, Yoshimi K, Asanuma M, Toyokuni S, Mochizuki H, Uchiyama Y, Hattori N, Iwai K. Possible involvement of iron-induced oxidative insults in neurodegeneration. Neurosci Lett. 2015 Feb 19;588:29-35.

    26． Tanaka Y, Ueno Y, Shimada Y, Yamashiro K, Tanaka R, Urabe T, Hattori N. Paradoxical brain embolism associated with Kimura disease mimics watershed infarction. J Stroke Cerebrovasc Dis. 2015 Feb;24(2):e55-7.

    27． Ueno Y, Koike M, Shimada Y, Shimura H, Hira K, Tanaka R, Uchiyama Y, Hattori N, Urabe T. L-carnitine enhances axonal plasticity and improves white-matter lesions after chronic hypoperfusion in rat brain. J Cereb Blood Flow Metab. 2015 Mar;35(3):382-91.

    28． Shimo Y, Nishina K, Hatano T, Hattori N. Sensory tricks for isolated speech-induced lingual dystonia. BMJ Case Rep. 2015 Mar 5;2015. pii: bcr2014208272.

    29． Nishikawa N, Shimo Y, Wada M, Hattori N, Kitazawa S. Effects of aging and idiopathic Parkinson’s disease on tactile temporal order judgment. PLoS One. 2015 Mar 11;10(3):e0118331.

    30． Funayama M, Ohe K, Amo T, Furuya N, Yamaguchi J, Saiki S, Li Y, Ogaki K, Ando M, Yoshino H, Tomiyama H, Nishioka K, Hasegawa K, Saiki H, Satake W, Mogushi K, Sasaki R, Kokubo Y, Kuzuhara S, Toda T, Mizuno Y, Uchiyama Y, Ohno K, Hattori N. CHCHD2 mutations in autosomal dominant late-onset Parkinson’s disease: a genome-wide linkage and sequencing study. Lancet Neurol. 2015 Mar;14(3):274-82.

    31． Yatomi Y, Tanaka R, Shimada Y, Yamashiro K, Liu M, Mitome-Mishima Y, Miyamoto N, Ueno Y, Urabe T, Hattori N. Type 2 diabetes reduces the proliferation and survival of oligodendrocyte progenitor cells in ishchemic white matter lesions. Neuroscience. 2015 Mar 19;289:214-23.

    32． Hatano T, Saiki S, Okuzumi A, Mohney RP, Hattori N. Identification of novel biomarkers for Parkinson’s disease by metabolomic technologies. J Neurol Neurosurg Psychiatry. 2015 Mar 20. pii: jnnp-2014-309676.

    33． Kawajiri S, Noda K, Ikeda A, Koinuma T, Tomizawa Y, Hattori N, Okuma Y. Low dose of clonazepam is effective in the treatment of painless legs and moving toes syndrome: a case report. Case Rep Neurol. 2015 Mar 21;7(1):59-62. doi: 10.1159/000380942. eCollection 2015 Jan-Apr. PubMed PMID: 25873890; PubMed Central PMCID: PMC4395820.

    34． Kobayashi M, Tanaka R, Yamashiro K, Ueno Y, Kato E, Miura S, Daida H, Hattori N. Pre-existing Mobile Cardiac Thrombus and the Risk of Early Recurrent Embolism after Intravenous Thrombolysis: A Case Report. J Stroke Cerebrovasc Dis. 2015 Jun;24(6):e161-3.

    35．Kino Y, Washizu C, Kurosawa M, Yamada M, Miyazaki H, Akagi T, Hashikawa T, Doi H, Takumi T, Hicks GG, Hattori N, Shimogori T, Nukina N. FUS/TLS deficiency causes behavioral and pathological abnormalities distinct from amyotrophic lateral sclerosis. Acta Neuropathol Commun. 2015 Apr 25;3:24.

    36．Mitsui J, Matsukawa T, Sasaki H, Yabe I, Matsushima M, Dürr A, Brice A, Goto J, Ichikawa Y, Nakahara Y, Momose Y, Takahashi Y, Hara K, Kakita A, Yamada M, Takahashi H, Onodera O, Nishizawa M, Watanabe H, Ito M, Sobue G, Ishikawa K, Mizusawa H, Kanai K, Hattori T, Kuwabara S, Arai K, Koyano S, Kuroiwa Y, Hasegawa K, Yuasa T, Yasui K, Nakashima K, Ito H, Izumi Y, Kaji R, Kato T, Kusunoki S, Osaki Y, Horiuchi M, Kondo T, Murayama S, Hattori N, Yamamoto M, Murata M, Satake W, Toda T, Filla A, Klockgether T, Wüllner U, Nicholson G, Gilman S, Tanner CM, Kukull WA, Stern MB, Lee VM, Trojanowski JQ, Masliah E, Low PA, Sandroni P, Ozelius LJ, Foroud T, Tsuji S. Variants associated with Gaucher disease in multiple system atrophy. Ann Clin Transl Neurol. 2015 Apr;2(4):417-26.

    37．Ueno Y, Yamashiro K, Tanaka Y, Watanabe M, Miyamoto N, Shimada Y, Kuroki T, Tanaka R, Miyauchi K, Daida H, Hattori N, Urabe T. Rosuvastatin may stabilize atherosclerotic aortic plaque: transesophageal echocardiographic　study in the EPISTEME trial. Atherosclerosis. 2015 Apr;239(2):476-82.

    38．Noda K, Hattori N, Okuma Y. Hemiballism with leg predominance caused by contralateral subthalamic haemorrhage. BMJ Case Rep. 2015 Apr 9;2015. pii: bcr2014208525.

    39．Vaikath NN, Majbour NK, Paleologou KE, Ardah MT, van Dam E, van de Berg WD, Forrest SL, Parkkinen L, Gai WP, Hattori N, Takanashi M, Lee SJ, Mann DM, Imai Y, Halliday GM, Li JY, El-Agnaf OM. Generation and characterization of novel conformation-specific monoclonal antibodies for α-synuclein pathology. Neurobiol Dis. 2015 Jul;79:81-99.

    40．Nishioka K, Oyama G, Yoshino H, Li Y, Matsushima T, Takeuchi C, Mochizuki Y, Mori-Yoshimura M, Murata M, Yamasita C, Nakamura N, Konishi Y, Ohi K, Ichikawa K, Terada T, Obi T, Funayama M, Saiki S, Hattori N. High frequency of beta-propeller protein-associated neurodegeneration (BPAN) among patients with intellectual disability and young-onset parkinsonism. Neurobiol Aging. 2015 May;36(5):2004.e9-2004.e15.

    41．Matsumoto G, Shimogori T, Hattori N, Nukina N. TBK1 controls autophagosomal engulfment of polyubiquitinated mitochondria through p62/SQSTM1 phosphorylation. Hum Mol Genet. 2015 Aug 1;24(15):4429-42.

    42．Shimo Y, Nakajima A, Hattori N. Dopamine agonist withdrawal syndrome in a patient with restless legs syndrome without impulse control disorder or drug abuse. Neurol Sci. 2015 Jun;36(6):1021-3.

    43．Fuse A, Furuya N, Kakuta S, Inose A, Sato M, Koike M, Saiki S, Hattori N. VPS29-VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process. FEBS Lett. 2015 Jun 4;589(13):1430-6.

    44．Matsushima T, Nishioka K, Tanaka R, Yokoyama K, Hattori N. Anterior opercular syndrome induced by Epstein-Barr virus encephalitis. Neurocase. 2015 Jun 1:1-6.[Epub ahead of print] PubMed PMID: 26027635.

    45．Funayama M, Hattori N. CHCHD2 and Parkinson’s disease–authors’ reply. Lancet Neurol. 2015 Jul;14(7):682-3.

    46．Fukae J, Higuchi MA, Yanamoto S, Fukuhara K, Tsugawa J, Ouma S, Hatano T, Yoritaka A, Okuma Y, Kashihara K, Hattori N, Tsuboi Y. Utility of the Japanese version of the 9-item Wearing-off Questionnaire. Clin Neurol Neurosurg. 2015 Jul;134:110-5.

    47．Takahashi M, Ikeda J, Tomida T, Hirata K, Hattori N, Inoue Y. Daytime symptoms of restless legs syndrome–clinical characteristics and rotigotine effectiveness. Sleep Med. 2015 Jul;16(7):871-6.

    48．Fujimaki M, Kawajiri S, Ichikawa K, Tomizawa Y, Nakazato T, Noda K, Hattori N, Koike M, Okuma Y. Lymphomatoid Granulomatosis with Central Nervous System Involvement Successfully Treated with Cyclophosphamide, High-dose Cytarabine, Irradiation: A Case Study. CNS Neurosci Ther. 2015 Jul;21(7):610-2.

    49．Tanaka R, Yamashiro K, Okuma Y, Shimura H, Nakamura S, Ueno Y, Tanaka Y, Miyamoto N, Tomizawa Y, Nakahara T, Furukawa Y, Watada H, Kawamori R, Hattori N, Urabe T. Effects of Pioglitazone for Secondary Stroke Prevention in Patients with Impaired Glucose Tolerance and Newly Diagnosed Diabetes: The J-SPIRIT Study. J Atheroscler Thromb. 2015 Aug 11. [Epub ahead of print] PubMed PMID: 26269002.

    50．Noda K, Nakajima S, Sasaki F, Ito Y, Kawajiri S, Tomizawa Y, Hattori N, Limb Monochorea.
    J Stroke Cerebrovasc Dis. 2015 Aug 17. pii: S1052-3057(15)00334-1.

    51．Kurosawa M, Matsumoto G, Sumikura H, Hatsuta H, Murayama S, Sakurai T, Shimogori T, Hattori N, Nukina N. Serine 403-phosphorylated p62/SQSTM1 immunoreactivity in inclusions of neurodegenerative diseases. Neurosci Res. 2015 Aug 21. pii: S0168-0102(15)00209-6.

    52．Yoritaka A, Kawajiri S, Yamamoto Y, Nakahara T, Ando M, Hashimoto K, Nagase M, Saito Y, Hattori N. Randomized, double-blind, placebo-controlled pilot trial of reduced coenzyme Q10 for Parkinson’s disease. Parkinsonism Relat Disord. 2015 Aug;21(8):911-6.

    53．Ueno S, Sekimoto-Tsuboi S, Ishiguro Y, Koinuma T, Eguchi H, Machida Y, Hattori N, Miwa H. Good’s syndrome with opportunistic infection of the central nervous system: a case report. BMC Neurol. 2015 Aug 25;15:150.

    54．Imai Y, Kobayashi Y, Inoshita T, Meng H, Arano T, Uemura K, Asano T, Yoshimi K, Zhang CL, Matsumoto G, Ohtsuka T, Kageyama R, Kiyonari H, Shioi G, Nukina N, Hattori N, Takahashi R. The Parkinson’s Disease-Associated Protein Kinase LRRK2 Modulates Notch Signaling through the Endosomal Pathway. PLoS Genet. 2015 Sep 10;11(9):e1005503.

    55．Nishioka K, Hayashi T, Suzuki M, Li Y, Nakayama S, Matsushima T, Usui C, Shibata N, Motoi Y, Tanaka R, Nishioka K, Hattori N. Fibromyalgia syndrome and cognitive dysfunction in elderly: a case series. Int J Rheum Dis. 2015 Sep 10. doi: 10.1111/1756-185X.12734. [Epub ahead of print]

    56．Noda K, Tosaka Y, Ishiguro Y, Kawajiri S, Tomizawa Y, Hattori N, Okuma Y. Delayed chorea after recovery from severe akinetic-rigid parkinsonism caused by extrapontine myelinolysis. J Neurol Sci. 2015 Sep 10. pii: S0022-510X(15)02107-3.

    57．Matsumoto SE, Motoi Y, Ishiguro K, Tabira T, Kametani F, Hasegawa M, Hattori N. The twenty-four KDa C-terminal tau fragment increases with aging in tauopathy mice: implications of prion-like properties. Hum Mol Genet. 2015 Sep 15. pii: ddv351. [Epub ahead of print]

    58．Bhidayasiri R, Hattori N, Jeon B, Chen RS, Lee MK, Bajwa JA, Mok VC, Zhang B, Syamsudin T, Tan LC, Jamora RD, Pisarnpong A, Poewe W. Asian perspectives on the recognition and management of levodopa ‘wearing-off’ in Parkinson’s disease. Expert Rev Neurother. 2015 Sep 21:1-13. [Epub ahead of print]

    59．Noda K, Kawajiri S, Tomizawa Y, Hattori N, Okuma Y. Pisa syndrome in progressive supranuclear palsy: A case report. Parkinsonism Relat Disord. 2015 Sep;21(9):1115-6.

    60．Yamashiro K, Tanaka R, Hoshino Y, Hatano T, Nishioka K, Hattori N. The prevalence and risk factors of cerebral microbleeds in patients with Parkinson’s disease. Parkinsonism Relat Disord. 2015 Sep;21(9):1076-81.

    61. Hojo M, Ohta K, Iikura M, Hirashima J, Sugiyama H, Takahashi K. The impact of co-existing seasonal allergic rhinitis caused by Japanese Cedar Pollinosis (SAR-JCP) upon asthma control status.Allergol Int. 2015 Apr; 64(2): 150-5.

    62. Iida T, Shiba M, Yohino I, Miyaoka E, Asamura H, Date H, Okumura M, Tada H, Nakanishi Y, Dosaka H, Kobayashi H, Takahashi K, Inoue M, Yokoi K. Surgical intervention for non–small-cell lung cancer patients with pleural carcinomatosis results from the Japanese lung cancer registry in 2004. Journal of Thoracic Oncology. 2015 Jul; 10(7): 1076-1082.

    63. Ichikawa M, Kodama Y, Yoshimi K, Shiota S, Kotajima M, Nakajyo M, Seyama K, Fukuchi Y, Takahashi K. Effects of transdermal tulobuterol on dyspnea and respiratory function during exercise in patients with chronic obstructive pulmonary disease. J Thorac Dis. 2015 Apr; 7(4): 687-96.Itoigawa Y, Harada N, Harada S, Katsura Y, Makino F, Ito J, Nurwidya F, Kato M, Takahashi F, Atsuta R, Takahashi K. TWEAK enhances TGF-β-induced epithelial-mesenchymal transition in human bronchial epithelial cells. Respir Res. 2015 Apr; 16(1): 48.

    64. Iwakami S, Fujii M, Tsutsumi T, Sekimoto Y, Jo H, Hara M, Iwakami N, Takahashi K. Autoimmune pulmonary alveolar proteinosis with primary lung cancer in a patient of very advanced years. Geriatr Gerontol Int. 2015 May; 15(5): 666-7.

    65. Ko R, Kenmotsu H, Hisamatsu Y, Akamatsu H, Omori S, Nakashima K, Oyakawa T, Wakuda K, Shukuya T, Ono A, Imai H, Taira T, Naito T, Murakami H, Mori K, Endo M, Ohde Y, Takahashi K, Takahashi T. The effect of gefitinib in patients with postoperative recurrent non-small cell lung cancer harboring mutations of the epidermal growth factor receptor.Int J Clin Oncol. 2015 Aug; 20(4): 668-73.

    66. Sekiya M, Yoshimi K, Muraki K, Iwakami S, Togo S, Tamaki S, Dambara T, Takahashi K. Do respiratory comorbidities limit the diagnostic usefulness of ultrasound-guided needle aspiration for subpleural lesions? Respir Investig. 2015 May; 53(3): 98-103.

    67. Shiota S, Ichikawa M, Suzuki K, Fukuchi Y, Takahashi K. Practical surrogate marker of pulmonary dysanapsis by simple spirometry: an observational case-control study in primary care. BMC Fam Prct. 2015 Mar; 16(1): 41.

    68. ya T, Ko R, Mori K, Kato M, Yagishita S, Kanemaru R, Honma Y, Shibayama R, Koyama R, Shimada N, Takahashi K. Prognostic factors in non-small cell lung cancer patients who are recommended to receive single-agent chemotherapy (docetaxel or pemetrexed) as a second- or third-line chemotherapy: in the era of oncogenic drivers and molecular-targeted agents. Cancer Chemother Pharmacol. 2015 Aug [Epub ahead of print]

    69. Sugano K, Okuyama T, Iida S, Komatsu H, Ishida T, Kusumoto S, Uchida M, Nakaguchi T, Kubota Y, Ito Y, Takahashi K, Akechi T. Medical Decision-Making Incapacity among Newly Diagnosed Older Patients with Hematological Malignancy Receiving First Line Chemotherapy: A Cross-Sectional Study of Patients and Physicians. PLoS One. 2015 Aug; 10(8): e0136163. doi: 10.1371

    70. Tobino K, Johkoh T, Fujimoto K, Sakai F, Arakawa H, Kurihara M, Kumasaka T, Koike K, Takahashi K, Seyama K. Computed tomographic features of lymphangioleiomyomatosis: Evaluation in 138 patients. Eur J Radiol. 2015 Mar; 84(3): 534-41.

    71. Tajima K, Yae T, Javaid S, Tam O, Comaills V, Morris R, Wittner BS, Liu M, Engstrom A, Takahashi F, Black JC, Ramaswamy S, Shioda T, Hammell M, Haber DA, Whetstine JR, Maheswaran S. SETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes. Nature Commun. 2015; 6: 8257

    72. Yagishita S, Fujita Y, Kitazono S, Ko R, Nakadate Y, Sawada T, Kitamura Y, Shimoyama T, Maeda Y, Takahashi F, Takahashi K, Tamura T, Koizumi F. Chemotherapy regulated microRNA-125/HER2 pathway as a novel therapeutic target for trastuzumab-mediated cellular cytotoxicity in small-cell lung cancer. Mol Cancer Ther. 2015 Jun; 14(6): 1414-23.

    73. Nonaka R, Iesaki T, de Vega S, Daida H, Okada T, Sasaki T, and Arikawa-Hirasawa E Perlecan deficiency causes endothelial dysfunction by reducing the expression of endothelial nitric oxide synthase. Physiol Rep. 2015 27;3. pii: e12272. IF:0.53

    74. Kerever A, Kamagata K, Yokosawa S, Otake Y, Ochi H, Yamada T, Hori M, Kamiya K, Nishikori A, Aoki S, Arikawa-Hirasawa E. See-through Brains and Diffusion Tensor MRI Clarified Fiber Connections: A Magnetic Resonance in Medical Sciences in press

    75. Iwata S, Ito M, Nakata T, Noguchi Y, Okuno T, Ohkawara B, Masuda A, Goto T, Adachi M, Osaka H, Nonaka R, Arikawa-Hirasawa E, Ohno K. A missense mutation in domain III in HSPG2 in Schwartz–Jampel syndrome compromises secretion of perlecan into the extracellular space　Neuromuscul Disord. 8. pii: S0960-8966(15)00153-4. 2015

    76. Kerever A, Yamada T, Suzuki Y Mercier F, Arikawa-Hirasawa, E　 Fractone aging in the subventricular zone of the lateral ventricle Journal of Chemical Neuroanatomy. 2015 In press

    77. Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, Li H, Li Q, Wang X, Uchiyama Y, Truttmann AC, Kroemer G, Puyal J, Blomgren K, Zhu C (in press) Neuroprotection by selective neuronal deletion of autophagy-related gene 7 in neonatal brain injury. Autophagy

    78. Rinchai D, Riyapa D, Buddhisa S, Utispan K, Titball RW, Stevens MP, Stevens JM, Ogawa M, Tanida I, Koike M, Uchiyama Y, Ato M, Lertmemongkolchai G (2015) Macroautophagy is essential for killing of intracellular Burkholderia pseudomallei in human neutrophils. Autophagy 11:748-755. doi: 10.1080/15548627.2015.1040969

    79. Funayama M, Ohe K, Amo T, Furuya N, Yamaguchi J, Saiki S, Li Y, Ogaki K, Ando M, Yoshino H, Tomiyama H, Nishioka K, Hasegawa K, Saiki H, Satake W, Mogushi K, Sasaki R, Kokubo Y, Kuzuhara S, Toda T, Mizuno Y, Uchiyama Y, Ohno K, Hattori N. (2015) CHCHD2 mutations in autosomal dominant late-onset Parkinson’s disease: a genome-wide linkage and sequencing study. Lancet Neurol, 14:274-282. doi: 10.1016/S1474-4422(14)70266-2. Epub 2015 Feb 4. PubMed PMID: 25662902

    80. Furuta A, Kikuchi H, Fujita H, Yamada D, Fujiwara Y, Kabuta T, Nishino I, Wada K, Uchiyama Y (2015) Property of Lysosomal Storage Disease associated with Midbrain Pathology in the CNS of LAMP-2-deficient Mice. Am J Pathol 185: 1713-1723, http://dx.doi.org/10.1016/j.ajpath.2015.02.015

    81. Nori S, Okada Y, Nishimura S, Ssaki T, Itakura G, Kobayashi Y, Renault-Mihara F, Shimizu A, Koya I, Yoshida R, Kudoh J, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Nakamura M, Okano H (2015) Long-Term Safety Issues of iPSC-Based Cell Therapy in a Spinal Cord Injury Model: Oncogenic Transformation with Epithelial-Mesenchymal Transition. Stem Cell Rep 4:1-14

    82. Uemura N, Koike M, Ansai K, Kinoshita M, Fujiwara-Ishikawa T, Matsui H, Naruse K, Sakamoto N, Uchiyama Y, Todo T, Takeda S, Yamakado H, Takahashi R (2015) Axonal accumulation of alpha-synuclein in Gaucher disease model of medaka (Oryzias latipes) does not contribute to neurodegeneration. Pros Genetics doi: 10.1371

    83. Nanao T, Koike M, Yamaguchi J, Sasaki M, Uchiyama Y (2015) Cellular localization and tissue distribution of endogenous DFCP1 protein. Biomed Res 36:121-133

    84. Tanida I, Ueno T, Uchiyama Y (2015) A Super-Ecliptic, pHluorin-mKate2, Tandem Fluorescent Protein-Tagged Human LC3 for the Monitoring of Mammalian Autophagy. PLoS ONE 9: e110600. doi:10.1371/journal.pone.0110600